Niceritrol CAS Registry Number: 5868-05-3 烟酸戊四醇酯
CAS Name: 3-Pyridinecarboxylic acid 2,2-bis[[(3-pyridinylcarbonyl)oxy]methyl]-1,3-propanediyl ester
Additional Names: nicotinic acid neopentanetetrayl ester; pentaerythritol tetranicotinateTrademarks: Perycit (Bofors); Bufor (Bofors)
Percent Composition: C 62.59%, H 4.35%, N 10.07%, O 23.00%
📌 参考资料/链接：
Literature References: Prepn: FR M2046 (1963 to Soc. d'Etudes et de Recherches Pharmacotechniques), C.A. 60, 10656e (1964); GB 1022880; GB 1053689 (1966, 1967 to Aktiebolag Bofors), C.A. 64, 19708d (1966), C.A. 66, 104907e (1967); Kuriyama, Kudo, JP 67 2359 (1967 to Yoshitomi), C.A. 66, 115935p (1967). Acute toxicity data: T. Sugawara et al., Oyo Yakuri 14, 741 (1977), C.A. 88, 131005v (1977).
📄 详细内容
Properties: Crystals, mp reported as 160-162° and as 163-164°. LD50 in mice, rats (g/kg): 20, 20 orally; 5, 5 s.c.; 5, 5 i.p.; in rabbits (g/kg): 10 orally; 5 i.p. (Sugawara).
Melting point: mp reported as 160-162° and as 163-164°
Toxicity data: LD50 in mice, rats (g/kg): 20, 20 orally; 5, 5 s.c.; 5, 5 i.p.; in rabbits (g/kg): 10 orally; 5 i.p. (Sugawara)
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Nicotinic Acid Derivatives.
产品链接: 5868-05-3››