CAS: 5868-05-3; Niceritrol

相似化合物

98326-19-3 4591-56-4 614-18-6

📜季戊四醇,氯化烟碱盐酸盐 以 吡啶 作为反应溶剂,化学反应 5.0H,以97%的收率获得产物季戊四醇四烟酸酯
参考文献:Gradual Increase In The Dimensionality Of Cobalt And Mercury Coordination Networks Based On Conformation Of Tetradentate Tectons
标题:Gradual Increase In The Dimensionality Of Cobalt And Mercury Coordination Networks Based On Conformation Of Tetradentate Tectons
摘要:我们制备了以季戊四醇骨架为基础,分别以四个烟酰基或异烟酰基为配位位点的中性四单齿构造子 1 和 2,并研究了它们在 Hgcl2 或 Cocl2(分别提供 "V "型或方型几何形状的金属酸盐构造子)存在时反应生成配位网络的能力.构造子 1 在同一平面上提供四个配位位点(正方形几何形状),在中性 Hgcl2 的存在下观测到一个 1-D 配位网络,而在 Cocl2 金属酸性构造子的存在下,其四个可用配位位点占据了正方形的四角,从而得到一个 2-D 中性配位网络.对于同样具有四个配位位点但占据假四面体顶点的金属对位体 2,在氯化汞存在下得到的是二维网络,而在氯化钴存在下观测到的是三维网络.在后一种情况下,观测到的是一种两重同源互穿结构.
DOI:10.1039/b301351K

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-10005720-B2
优先权日:2013-04-05
标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same
发明人：SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L
权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL
摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

专利号:US-2018370905-A1
优先权日:2013-04-05
标题:Compounds Useful for the Treatment of Metabolic Disorders and Synthesis of the Same

专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

专利号:US-10099998-B2
优先权日:2015-02-04
标 题 :Compound, and separation method, synthesis method and use thereof
发明人：DUAN ZHENWEN; GUO SHUREN; LI XUEMEI
权利人:BEIJING PEKING UNIV WBL BIOTECH CO LTD
摘要:The invention relates to new compounds as well as a separation method, a synthetic method and use thereof. It is demonstrated by an assay on activity that the compound has an activity of inhibiting an HMG-CoA reductase. In addition, the invention also relates to a derivative of the compound.

专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications