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Stepronin CAS Registry Number: 72324-18-6 司替罗宁

CAS Name: N-[1-Oxo-2-[(2-thienylcarbonyl)thio]propyl]glycine
Additional Names: 2-(a-thenoylthio)propionylglycine; N-(2-mercaptopropionyl)glycine 2-thiophenecarboxylate (ester); TTPG; prostenoglycine
Trademarks: Tiase (Mediolanum)
Percent Composition: C 43.94%, H 4.06%, N 5.12%, O 23.41%, S 23.46%

📌 参考资料/链接：
Literature References: Prepn, properties and toxicology: F. Bolasco, BE 875186; eidem, US 4242354 (1979, 1980 to Mediolanum Farmaceutici). Clinical trials in bronchitis: M. Lingetti et al., Int. J. Clin. Pharmacol. Res. 1, 273 (1981); F. Dotta et al., Clin. Ter. 105, 307 (1983); G. C. Morandini et al., Curr. Ther. Res. 35, 783 (1984). Effect on human lung mucus: M. C. Morale et al., Int. J. Tissue React. 5, 231 (1983).

📄 详细内容

Properties: Colorless crystals from acetonitrile, mp 168-170°. uv max: 292 nm. LD50 in mice (mg/kg): 2500 orally, 1250 i.v.; in rats (mg/kg): 2500 orally, 1801 i.m. (Bolasco).
Melting point: mp 168-170°
Absorption maximum: uv max: 292 nm
Toxicity data: LD50 in mice (mg/kg): 2500 orally, 1250 i.v.; in rats (mg/kg): 2500 orally, 1801 i.m. (Bolasco)
Derivative Type: Lysine salt
CAS Registry Number: 113790-28-6
Trademarks: Masor (Formenti); Mucodil (Valeas)
Derivative Type: Sodium salt
CAS Registry Number: 78126-10-0
Trademarks: Broncoplus (Sigma-Tau); Tioten (Mediolanum)
Percent Composition: C 40.67%, H 3.41%, N 4.74%, Na 7.78%, O 21.67%, S 21.72%
Therap-Cat: Mucolytic.
Keywords: Mucolytic.
产品链接: 72324-18-6››

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