CAS: 72324-18-6; 2-(2-((Thiophene-2-Carbonyl)Thio)Propanamido)Acetic Acid

该化合物是一种属于合成有机分子类的化学化合物,主要因其潜在的药理特性而得到承认,特别是在心血管健康方面;Stepronin已知具有血管效应,有助于改善血液循环和减少血管抗药性;该化合物还可能具有抗氧化特性,有助于其治疗用途;就其物理特性而言,Stepronin通常以白色为白,以非白色晶状粉形式出现,在某些有机溶剂中可溶解;其分子结构包括具体的功能组,便利其与生物系统的互动;与许多化学物质一样,Stepronin的安全特征和潜在副作用是使用该物质的重要考虑因素,需要进行彻底的研究和临床评估;

结构式图片

合成工艺路线路线简述

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    专利号:US-2014378538-A1
    优先权日:2011-12-14
    标 题:Methods of responding to a biothreat
    发明人:BANCEL STEPHANE
    权利人:MODERMA THERAPEUTICS INC
    摘要:The present disclosure provides for devices, in particular mobile devices, which may be used in the synthesis of modified nucleic acid molecules, in particular modified mRNA molecules. The device for making the modified nucleosides, modified nucleotides and modified nucleic acids (e.g., mRNA) disclosed herein may be mobile devices comprising at least one sample block for insertion of one or more sample vessels, a device base with electronic control units for the sample block, a voltage supply, and one or more reagent(s) for the synthesis of at least one nucleic acid.

    专利号:US-9790531-B2
    优先权日:2012-08-14
    标 题 :Enzymes and polymerases for the synthesis of RNA
    发明人:WANG YUXUN; RAMAKRISHNAN DIVAKAR; DE FOUGEROLLES ANTONIN; WHORISKEY SUSAN
    权利人:MODERNATX INC
    摘要:The invention relates to compositions and methods for the design, evolution, preparation, and/or manufacture of enzymes for use with polynucleotides, primary transcripts and mmRNA molecules.

    专利号:US-2024002331-A1
    优先权日:2022-06-08
    标 题 :Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
    发明人:ALI MIR; BOESCH AUSTIN WAYNE; DRUMMOND DARYL CLARK; KUHLMAN WILLIAM; NIELSEN ULRIK
    权利人:TIDAL THERAPEUTICS INC
    摘要:Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., immune cells), and methods of making and using such lipids and targeted lipid nanoparticles.

    专利号:US-2025205169-A1
    优先权日:2023-12-13
    标 题:Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
    发明人:ALI MIR
    权利人:TIDAL THERAPEUTICS INC
    摘要:Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., immune cells), and methods of making and using such lipids and targeted lipid nanoparticles.

    专利号:US-2015211039-A1
    优先权日:2012-08-14
    标题:Enzymes and polymerases for the synthesis of rna

    专利号:WO-2014028429-A2
    优先权日:2012-08-14
    标 题 :Enzymes and polymerases for the synthesis of rna
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    主要参考文献


    1: de Giorgi L, Habeshaw JA, Broadhurst K, Carminati P, Oxford JS. Anti-human immunodeficiency virus activity of a new immunosuppressant drug called stepronin. Transplant Proc. 1999 Dec;31(8):3257. Italian. Italian. Italian. Italian. Italian. Italian. Italian.

    合成参考文献


    摘要:Medicamentos de Actualidad., 20(310), 1984
    参考文献:10.1007/bf00987337
    摘要:MEIXNER H. Malignant arrhenoblastoma. Arch Gynakol. 1958;191(1):31–6. doi: 10.1007/bf00987337.
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