网站主页>>>项目整合精选>>>项目整合精选>>>Eprazinone CAS Registry Number: 10402-90-1 盐酸依普拉酮

Eprazinone CAS Registry Number: 10402-90-1 盐酸依普拉酮

CAS Name: 3-[4-(2-Ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-1-propanone
Additional Names: 3-[4-(b-ethoxyphenethyl)-1-piperazinyl]-2-methylpropiophenone
Percent Composition: C 75.75%, H 8.48%, N 7.36%, O 8.41%

📌 参考资料/链接：
Literature References: Prepn of the dihydrochloride: R. Y. Mauvernay, NL 6602581; idem, US 3448192 (1966, 1969 both to Riom). Pharmacodynamics: J. Vacher et al., Arch. Int. Pharmacodyn. Ther. 165, 1 (1967). Pharmacological study: Y. Kase et al., Nippon Yakurigaku Zasshi 73, 605 (1977), C.A. 88, 15657 (1978). Efficacy: W. Spitzer, Fortschr. Med. 98, 871 (1980). Metabolism: P. Toffel-Nadolny, W. Gielsdorf, Arzneim.-Forsch. 31, 719 (1981).

📄 详细内容

Derivative Type: Dihydrochloride
CAS Registry Number: 10402-53-6Trademarks: Eftapan (Merckle); Mucitux (Riom)
Percent Composition: C 63.57%, H 7.56%, N 6.18%, O 7.06%, Cl 15.64%
Properties: White, bitter-tasting crystalline powder, mp 201° (Toffel-Nadolny, Gielsdorf); also reported as crystals from methanol, mp 160° (Mauvernay). LD50 in mice (mg/kg): 729 orally, 38 i.v. (Vacher).
Melting point: mp 201° (Toffel-Nadolny, Gielsdorf); mp 160° (Mauvernay)
Toxicity data: LD50 in mice (mg/kg): 729 orally, 38 i.v. (Vacher)
Therap-Cat: Antitussive.
Keywords: Antitussive.
产品链接: 10402-90-1››

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