Properties: Liquid, bp0.11 178-182°.
Boiling point: bp0.11 178-182°
Derivative Type: Sulfate
CAS Registry Number: 149-15-5
Trademarks: Butyn Sulfate (Abbott)
Percent Composition: C 60.82%, H 8.79%, N 7.88%, O 18.00%, S 4.51%
Properties: Crystals from n-propanol, mp 138.5-139.5°. Also reported as mp 100-103°. Produces numbness of tongue on tasting. Affected by light. One gram dissolves slowly in somewhat less than 1 ml water, more rapidly on heating. Quite sol in warm alc, in acetone; slightly sol in chloroform. Practically insol in ether. Aq soln is practically neutral to litmus and may be boiled for sterilization without dec. LD50 i.v. in mice: 12.4 mg/kg (Schmidt). Pharmaceutical Incompat. Alkalies and alkaline-reacting substances liberate the free base as an oily liquid from solns. Bicarbonates produce a precipitate of butacaine carbonate. Iodine gives a brown precipitate. Chlorides form the almost insol butacaine chloride which may precipitate.
Melting point: mp 138.5-139.5°; mp 100-103°
Toxicity data: LD50 i.v. in mice: 12.4 mg/kg (Schmidt)
Derivative Type: Hydrochloride
Percent Composition: C 63.05%, H 9.11%, N 8.17%, O 9.33%, Cl 10.34%
Properties: Crystals from ethanol, mp 157-158.5°.
Melting point: mp 157-158.5°
Therap-Cat: Anesthetic (local).
Therap-Cat-Vet: Anesthetic (local).
Keywords: Anesthetic (Local).
产品链接: 149-16-6››