Amocarzine CAS Registry Number: 36590-19-9 4-甲基-N-[4-[(4-硝基苯基)氨基]苯基]-1-哌嗪硫代甲酰胺
CAS Name: 4-Methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-1-piperazinecarbothioamide
Additional Names: 4-nitro-4'-[(N-methylpiperazinyl)thiocarbonylamino]diphenylaminePercent Composition: C 58.20%, H 5.70%, N 18.85%, O 8.61%, S 8.63%
📌 参考资料/链接：
Literature References: Orally active macrofilaricide; derivative of amoscanate, q.v. Prepn: BE 772053 (1971 to Agripat); R. Spaun et al., US 3781290 (1973 to Ciba-Geigy). Mechanism of action study: K. P. Davies et al., Exp. Parasitol. 68, 382 (1989). HPLC determn in biological fluids: S. C. Bhatia et al., J. Chromatogr. 434, 288 (1988). Pharmacokinetics: J. B. Lecaillon et al., Br. J. Clin. Pharmacol. 30, 625, 629 (1990). Clinical trial in onchocerciasis: A. A. Poltera et al., Lancet 337, 583 (1991).
📄 详细内容
Properties: mp 191-196°. Sol in acetonitrile.
Melting point: mp 191-196°
Therap-Cat: Anthelmintic (Nematodes).
Keywords: Anthelmintic (Nematodes).
产品链接: 36590-19-9››