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Oleanolic Acid CAS Registry Number: 508-02-1 齐墩果酸


CAS Name: (3b)-3-Hydroxyolean-12-en-28-oic acid
Additional Names: oleanol; caryophyllin
Percent Composition: C 78.90%, H 10.59%, O 10.51%
📌 参考资料/链接:
Literature References: Occurs in the free state in leaves of Olea europaea, Oleaceae, in leaves of Viscum album L., Loranthaceae, in buds of Syzygium aromaticum (L.) Merr. Perry, Myrtaceae (cloves), in Swertia japonica (Maxim.) Makino, and in Centaurium umbellatum Gilib. (Erythraea centaurium (L.) Pers.), Gentianaceae; as acetate in birch bark, as glycoside in many saponins. Isoln procedures (from cloves): Winterstein, Stein, Z. Physiol. Chem. 202, 222 (1931); Ruzicka, Hofmann, Helv. Chim. Acta 19, 114 (1936); Picard et al., J. Chem. Soc. 1939, 1047. Structure: Ruzicka et al., Helv. Chim. Acta 29, 210 (1946). Review: J. Simonsen, W. C. T. Ross, The Terpenes vol. 5 (University Press, Cambridge, 1957) pp 221-285. Cf. a- and b-amyrin.

📄 详细内容


Properties: Fine, solvated needles from alc. After drying, mp 310°. [a]D20 +83.3° (c = 0.6 in chloroform). pK 2.52. Insol in water. Sol in 65 parts ether, 106 parts 95% alcohol, 35 parts boiling 95% alcohol, 118 parts chloroform, 180 parts acetone, 235 parts methanol.
Melting point: mp 310°
pKa: pK 2.52
Optical Rotation: [a]D20 +83.3° (c = 0.6 in chloroform)
Derivative Type: Acetate
Percent Composition: C 77.06%, H 10.10%, O 12.83%
Properties: Needles from methanol, mp 268°. [a]D17 +74.5° (c = 0.6 in CHCl3).
Melting point: mp 268°
Optical Rotation: [a]D17 +74.5° (c = 0.6 in CHCl3)
Derivative Type: Methyl ester
Percent Composition: C 79.10%, H 10.71%, O 10.20%
Properties: mp 201°. [a]D20 +75° (c = 0.6 in CHCl3).
Melting point: mp 201°
Optical Rotation: [a]D20 +75° (c = 0.6 in CHCl3)
Derivative Type: Acetate of methyl ester
Percent Composition: C 77.30%, H 10.22%, O 12.48%
Properties: Needles from alcohol, mp 223°. [a]D20 +70° (c = 0.6 in CHCl3).
Melting point: mp 223°
Optical Rotation: [a]D20 +70° (c = 0.6 in CHCl3)
产品链接: 508-02-1››