Ipsapirone CAS Registry Number: 95847-70-4 伊沙匹隆
CAS Name: 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazolin-3(2H)-one 1,1-dioxide
Additional Names: isapirone
Percent Composition: C 56.84%, H 5.77%, N 17.44%, O 11.96%, S 7.99%
📌 参考资料/链接：
Literature References: Nonbenzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist. Prepn: W. Dompert et al., DE 3321969; P.-R. Seidel et al., US 4818756 (1984, 1989 both to Troponwerke). Pharmacology and serotonin (5-HT1) receptor binding study: J. Traber et al., Brain Res. Bull. 12, 741 (1984). 5-HT1 specific binding activity: W. U. Dompert et al., Arch. Pharmacol. 328, 467 (1985); T. Glaser, J. Traber, ibid. 329, 211 (1985). Behavioral effects in mice: R. J. DeSouza et al., Br. J. Pharmacol. 89, 377 (1986). Neurophysiological effects in comparison with buspirone. M. J. Rowan, R. Anwyl, Eur. J. Pharmacol. 132, 93 (1987). HPLC determn in biological samples: G. Bianchi, S. Caccia, J. Chromatogr. 431, 477 (1988).
📄 详细内容
Properties: Crystals from isopropanol, mp 137-138°.
Melting point: mp 137-138°
Derivative Type: Hydrochloride
CAS Registry Number: 92589-98-5Percent Composition: C 52.11%, H 5.52%, N 15.99%, O 10.96%, S 7.32%, Cl 8.10%
Properties: Crystals from isopropanol, mp 221-222°.
Melting point: mp 221-222°
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic; Arylpiperazines; Serotonin Receptor Agonist.
产品链接: 95847-70-4››