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Picumast CAS Registry Number: 39577-19-0 哌香豆司特

CAS Name: 7-[3-[4-[(4-Chlorophenyl)methyl]-1-piperazinyl]propoxy]-3,4-dimethyl-2H-1-benzopyran-2-one
Additional Names: 7-[3-[4-(p-chlorobenzyl)-1-piperazinyl]propoxy]-3,4-dimethylcoumarin; 1-(4-chlorobenzyl)-4-[3-(3,4-dimethylcoumarin-7-yloxy)propyl]piperazine
Percent Composition: C 68.09%, H 6.63%, Cl 8.04%, N 6.35%, O 10.88%

📌 参考资料/链接：
Literature References: Mast cell degranulation inhibitor with histamine antagonist activity. Prepn: E. C. Witte et al., DE 2123924; eidem, US 3810898 (1972, 1974 both to Boehringer, Mann.); E. C. Witte, Arzneim.-Forsch. 39, 1309 (1989). Mechanism of action studies: O. H. Wilhelms, Int. Arch. Allergy Appl. Immunol. 82, 544, 547 (1987). Series of articles on pharmacology, pharmacokinetics, and clinical trials: Arzneim.-Forsch. 39, 1307-1376 (1989).

📄 详细内容

Properties: Crystals from isopropanol, mp 112-114° (Witte, 1974); also reported as mp 115-117° (Witte, 1989).
Melting point: mp 112-114° (Witte, 1974); mp 115-117° (Witte, 1989)
Derivative Type: Dihydrochloride
CAS Registry Number: 39577-20-3Trademarks: Auteral (Boehringer, Mann.)
Percent Composition: C 58.43%, H 6.08%, Cl 20.70%, N 5.45%, O 9.34%
Properties: Crystals from aq ethanol, mp 266-268°.
Melting point: mp 266-268°
Therap-Cat: Antiallergic.
Keywords: Antiallergic.
产品链接: 39577-19-0››

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