CAS: 39577-19-0; Picumas

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      专利号:US-7919505-B2
      优先权日:2006-07-11
      标题 :Xinafoate salt of a substituted 5-oxazol-2-yl-quinoline compound
      发明人:TING PAULINE C; LEE JOE F; FENG KUNG-I; REEDER MICHAEL R; TRZASKA SCOTT T; ZHU MAN; MAO CHEN; FILIPOV DIMITAR L; ZARKADAS DIMITRIOS N
      权利人:SCHERING CORP
      摘要:The present invention relates to the compound of the formula n nTo methods of treating upper and lower obstructive airway diseases using said compound, to formulations comprising it, and to polymorphs and processes of synthesis of the polymorphic forms.

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      1: Hingorani M, Lightman S. Therapeutic options in ocular allergic disease. Drugs. 1995 Aug;50(2):208-21. doi: 10.2165/00003495-199550020-00002. 33(1-2):71-5. doi: 10.1007/BF01993130. 21 Suppl
      3:39-44. doi: 10.1111/j.1365-2222.1991.tb01762.x. 21 Suppl
      3:17-22. doi: 10.1111/j.1365-2222.1991.tb01759.x.

      合成参考文献


      参考文献:10.1159/000234276
      摘要:Wilhelms OH. Inhibition profiles of picumast and ketotifen on the in vitro release of prostanoids, slow-reacting substance of anaphylaxis, histamine and enzyme from human leukocytes and rat alveolar macrophages. Int Arch Allergy Appl Immunol. 1987;82(3-4):547–9. doi: 10.1159/000234276.
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