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项目整合精选>>>Narcotoline CAS Registry Number: 521-40-4 [S-(R*,R*)]-6,7-二甲氧基-3-(5,6,7,8-四氢-4-羟基-6-甲基-1,3-二氧杂环戊并[4,5-g]异喹啉-5-基)苯酞
Narcotoline CAS Registry Number: 521-40-4 [S-(R*,R*)]-6,7-二甲氧基-3-(5,6,7,8-四氢-4-羟基-6-甲基-1,3-二氧杂环戊并[4,5-g]异喹啉-5-基)苯酞
CAS Name: (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
Additional Names: desmethylnarcotine
Percent Composition: C 63.15%, H 5.30%, N 3.51%, O 28.04%
📌 参考资料/链接：
Literature References: Found in the shell of ripe poppyseed capsules: Wrede, Arch. Pharmacol. 184, 331 (1937); Baumgarten, Christ, Pharmazie 5, 80 (1950); Pfeifer, Weiss, ibid. 10, 658 (1955); from opium prepns: Pfeifer, Arch. Pharm. 290, 209 (1957). Preliminary stereochemical studies: Battersby, Spenser, J. Chem. Soc. 1965, 1087. Revised stereochemistry: Blaha et al., Collect. Czech. Chem. Commun. 29, 2328 (1964); Snatzke et al., Tetrahedron 25, 5059 (1969).
📄 详细内容
Properties: Rectangular rods from dil methanol, mp 202°. [a]D20 -189° (0.1 g in 25 ml chloroform, 20 cm tube). [a]D20 +5.8° (0.065 g in 5 ml 0.1N HCl in 20 cm tube). Very sparingly sol in water. Moderately sol in warm alc and ether. Freely sol in chloroform, in dil acids and in dil aq solns of KOH and NaOH. Sparingly sol in dil aq solns of Na2CO3.
Melting point: mp 202°
Optical Rotation: [a]D20 -189° (0.1 g in 25 ml chloroform, 20 cm tube); [a]D20 +5.8° (0.065 g in 5 ml 0.1N HCl in 20 cm tube)
产品链接: 521-40-4››