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Tolbutamide CAS Registry Number: 64-77-7 甲苯磺丁脲

CAS Name: N-[(Butylamino)carbonyl]-4-methylbenzenesulfonamide
Additional Names: 1-butyl-3-(p-tolylsulfonyl)urea; tolylsulfonylbutylurea; 3-(p-tolyl-4-sulfonyl)-1-butylurea; N-n-butyl-N'-tosylurea; N'-4-methylbenzenesulfonyl-N''-butylurea; N-(sulfonyl-p-methylbenzene)-N'-n-butylureaTrademarks: Artosin (Roche); Diaben (Chugai); Dolipol (Aventis); Mobenol (Church Dwight); Orabet (Berlin-Chemie); Orinase (Pharmacia Upjohn); Oterben (Chinoin); Pramidex (Hospira); Rastinon (Aventis)
Percent Composition: C 53.31%, H 6.71%, N 10.36%, O 17.75%, S 11.86%

📌 参考资料/链接：
Literature References: Description: Ehrhart, Naturwissenschaften 43, 93 (1956). Prepn: GB 808071; Aumüller, Herr, DE 1066575 (both 1959 to Hoechst); Ruschig et al., US 2968158 (1961 to Upjohn). Comprehensive description: W. F. Beyer, E. H. Jensen, Anal. Profiles Drug Subs. 3, 513-543 (1974).

📄 详细内容

Properties: Crystals, mp 128.5-129.5°.
Melting point: mp 128.5-129.5°
Derivative Type: Sodium salt
CAS Registry Number: 473-41-6
Percent Composition: C 49.30%, H 5.86%, N 9.58%, Na 7.86%, O 16.42%, S 10.97%
Properties: mp 130-133°. Tetrahydrate, mp 41-43°.
Melting point: mp 130-133°; mp 41-43°
Therap-Cat: Antidiabetic.
Therap-Cat-Vet: Hypoglycemic agent.
Keywords: Antidiabetic; Sulfonylurea Derivatives.
产品链接: 64-77-7››

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