其它产品项目整合

项目整合的本质是一项集合成方法学、反应工程学与过程分析技术于一体的系统工程。其核心逻辑可以概括为以下几点：源头优选：利用如N-硝胺化学等底层方法学突破，从分子层面颠覆传统高成本、高污染路线。过程强化：依托连续流技术，攻克有机金属试剂应用、光化学反应放大等“不可能”任务，实现高危工艺的本质安全。系统集成：整合“反应-淬灭-分离”全流程，利用微流控与在线分析技术，消除批次间的差异，实现药品制造的连续化与智能化。当前，中间体工艺研发正在经历从“经验驱动”向“数据驱动”的转变。AI辅助路线设计、自动化高通量筛选与连续制造平台的结合，将使得“分子结构与最优工艺路径”之间的映射关系逐渐清晰。未来的竞争优势，将属于那些能够将底层化学创新与先进工程技术进行无缝整合的研发体系。
备注: 根据相关法律法规, 本站点不显示有法律约束管制的产品, 如有遗漏, 请自行鉴别,或提交我们及时更新撤除.
如有产品相关项目调研推广服务, 请致函联系我们

客户展示

其它产品项目整合

Cupric Citrate CAS Registry Number: 866-82-0 柠檬酸铜

CAS Name: 2-Hydroxy-1,2,3-propanetricarboxylic acid copper (2+) salt (1:2)
Trademarks: Cuprocitrol
Percent Composition: C 22.86%, H 1.28%, Cu 40.32%, O 35.53%
Literature References: Prepd by the interaction of hot aq solns of CuSO4 and Na citrate: U.S.D. 25th ed., p 1653.

Salinazid CAS Registry Number: 495-84-1 2-异丙基噻吨酮

CAS Name: [(2-Hydroxyphenyl)methylene]hydrazide 4-pyridinecarboxylic acid
Additional Names: 1-isonicotinoyl-2-salicylidenehydrazine; isonicotinic acid salicylidenehydrazide; saliniazid; N'-o-hy...
Literature References: Prepd by the interaction of isoniazid and salicyl-aldehyde in water: Hart et al., Antibiot. Chemother. 4, 803 (1954); cf. Yale et al., J. Am. Chem. Soc. 75, 1933 (1953). Tuberculostatic activity and toxicity: Bavin et al., J. Pharm. Pharmacol. 7, 1032 (1955).

n-Butylmalonic Acid CAS Registry Number: 534-59-8 丁基丙二酸

CAS Name: Butylpropanedioic acid
Additional Names: pentane-1,1-dicarboxylic acid
Percent Composition: C 52.49%, H 7.55%, O 39.96%
Literature References: Prepd by the interaction of sodium n-amyl chloride and carbon dioxide under pressure with ligroin as solvent: Morton et al., J. Am. Chem. Soc. 58, 754 (1936).

Amiphenazole CAS Registry Number: 490-55-1 阿米苯唑

CAS Name: 5-Phenyl-2,4-thiazolediamine
Additional Names: 2,4-diamino-5-phenylthiazole; DAPT; phenamizole
Trademarks: Dizol; Daptazole (Nicholas); Daptazile; Fenamizol
Percent Composition:...
Literature References: Prepd by the interaction of thiourea and a-bromobenzyl cyanide in alcohol: Davies et al., J. Chem. Soc. 1950, 3491; from thiourea and a-cyanobenzyl benzenesulfonate in acetone: Dodson, Turner, J. Am. Chem. Soc. 73, 4517 (1951).

Diethylzinc CAS Registry Number: 557-20-0 二乙基锌

Additional Names: Zinc diethyl
Percent Composition: C 38.89%, H 8.16%, Zn 52.95%
Literature References: Prepd by the interaction of zinc and ethyl iodide: Simonowitch, Chem. Zentralbl. 1899, I, 1066; Lachmann, Am. Chem. J. 24, 32 (1900); Dennis, Hance, J. Am. Chem. Soc. 47, 370 (1925); from zinc and ethyl bromide, ethyl iodide: C. R. Noller, Org. Synth. coll. vol. II, 184. Used in synthesis of cyclopropanes: J. Furukawa et al., Tetrahedron 24, 53 (1968); eidem, Tetrahedron Lett. 1968, 3495; in synthesis of ketocarbenes: L. T. Scott, W. D. Cotton, J. Am. Chem. Soc. 95, 2708 (1973); in ring expansion of arenes: S. Miyano, H. Hashimoto, Chem. Commun. 1973, 216; in preservation of papers: J. C. Williams, G. B. Kelly Jr., US 3969549 (1976 to U.S.A.); eidem in Adv. Chem. Ser. 193, entitled "Preservation of Paper and Textiles of Historic and Artistic Value 2," J. C. Williams, Ed. (ACS, Washington DC, 1981) pp 109-117.

Dimethylzinc CAS Registry Number: 544-97-8 二甲基锌

Additional Names: Zinc dimethyl
Percent Composition: C 25.16%, H 6.33%, Zn 68.51%
Literature References: Prepd by the interaction of zinc and methyl iodide: Simonowitch, Chem. Zentralbl. 1899, I, 1066; Bamford et al., J. Chem. Soc. 1946, 468.

o-Nitrophenol CAS Registry Number: 88-75-5 邻硝基苯酚

Additional Names: 2-Nitrophenol
Percent Composition: C 51.80%, H 3.62%, N 10.07%, O 34.50%
Literature References: Prepd by the nitration of phenol; separated by steam distillation. Review of toxicology and human exposure: Toxicological Profile for Nitrophenols: 2-Nitrophenol and 4-Nitrophenol (PB93-110823, 1992) 131 pp.

Mestanolone CAS Registry Number: 521-11-9 美雄诺龙

CAS Name: (5a,17b)-17-Hydroxy-17-methylandrostan-3-one
Additional Names: 17b-hydroxy-17a-methyl-3-androstanone; 17a-methylandrostan-17b-ol-3-one; 17a-methylandrostan-3-on-17b-ol
Trademarks: ...
Literature References: Prepd by the oxidation of 17-methyl-3,17-androstanediol: Ruzicka et al., Helv. Chim. Acta 18, 1487 (1935); CH 208080 (1940 to Ciba).

Hydroquinone CAS Registry Number: 123-31-9 对苯二酚

CAS Name: 1,4-Benzenediol
Additional Names: p-dihydroxybenzene; hydroquinol; quinol
Trademarks: Aida (Paraphar); Black and White Bleaching Cream (Plough); Eldoquin (Valeant); Eldopaque (Vale...
Literature References: Prepd by the oxidation of aniline: L. Gattermann, T. Wieland, Die Praxis des Organischen Chemikers (de Gruyter, Berlin, 40th ed., 1961) p 266; by reduction of quinone: Kitchen, US 1322580 (1920); Seyewetz, Miodon, Bull. Soc. Chim. Fr. 33, 449 (1923); by Elbs persulfate oxidation of phenol: Baker, Brown, J. Chem. Soc. 1948, 2303; Forrest, Petrow, ibid. 1950, 2340; from acetylene + CO: Howk, Sauer, US 3055949 (1962 to du Pont). Toxicity data: Woodard et al., Fed. Proc. 8, 348 (1949). Toxicology and carcinogenicity study: F. W. Kari et al., Food Chem. Toxicol. 30, 737 (1992). Review: J. Varagnat in Kirk-Othmer Encyclopedia of Chemical Technology vol. 13 (Wiley-Interscience, New York, 3rd ed., 1981) pp 39-69.

Tolan CAS Registry Number: 501-65-5 二苯乙炔

CAS Name: 1,1'-(1,2-Ethynediyl)bisbenzene
Additional Names: diphenylacetylene; diphenylethyne
Percent Composition: C 94.34%, H 5.66%
Literature References: Prepd by the oxidation of benzil dihydrazone with mercuric oxide: Schlenk, Bergmann, Ann. 463, 76 (1928); by dehydrohalogenation of stilbene dibromide: Söderbäck, Ann. 443, 161 (1925); Smith, Hoehn, J. Am. Chem. Soc. 63, 1180 (1941); Smith, Falkof, Org. Synth. coll. vol. III, 350 (1955). Improved procedure: L. F. Fieser, Experiments in Organic Chemistry (Boston, 3rd ed., 1955) p 181.