Nebivolol CAS# 118457-14-0 奈比洛尔
Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and, in Europe, also for left ventricular failure. It is highly cardioselective under certain circumstances.
📌 参考资料/链接:
Sheth, Rakesh; Attanti, Srinivasarao Veeravenkata; Patel, Hasmukh Mathurbhai; Gupta, Vinodkumar; Nadkarni, Sunil Sadanand. Process for preparation of Nebivolol from 6-fluoro-3,4-dihydro-α-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol and 6-fluoro-3,4-dihydro-2-oxiranyl-2H-benzopyran. Assignee Torrent Pharmaceuticals Limited, India. WO 2006025070. (2006).
📄 详细内容
CAS No. 118457-14-0 奈比洛尔Nebivolol synthetic routes

Sheth, Rakesh; Attanti, Srinivasarao Veeravenkata; Patel, Hasmukh Mathurbhai; Gupta, Vinodkumar; Nadkarni, Sunil Sadanand. Process for preparation of Nebivolol from 6-fluoro-3,4-dihydro-α-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol and 6-fluoro-3,4-dihydro-2-oxiranyl-2H-benzopyran. Assignee Torrent Pharmaceuticals Limited, India. WO 2006025070. (2006).
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