Dabigatran etexilate mesylate CAS# 872728-81-9 甲磺酸达比加群酯
Dabigatran etexilate, also known as BIBR 1048MS, is a direct thrombin inhibitor. Dabigatran is used to prevent strokes in those with atrial fibrillation not caused by heart valve issues, as well as deep vein thrombosis and pulmonary embolism in persons who have been treated for 5–10 days with parenteral anticoagulant (usually low molecular weight heparin), and to prevent deep vein thrombosis and pulmonary embolism in some circumstances. It appears to be as effective as warfarin in preventing nonhemorrhagic strokes and embolic events in those with atrial fibrillation not due to valve problems.
📌 参考资料/链接:
Devarasetty, Sitaramaiah; Janni, Ravi; Nunna, Rambabu; Suraparaju, Raghu Ram. An improved process for the preparation of Dabigatran Etexilate mesylate and synthesis of its impurities. Pharma Chemica. Volume 10. Issue 4. Pages 127-148. Journal; Online Computer File. (2018).
📄 详细内容
CAS No. 872728-81-9 甲磺酸达比加群酯Dabigatran etexilate mesylate synthetic routes

Devarasetty, Sitaramaiah; Janni, Ravi; Nunna, Rambabu; Suraparaju, Raghu Ram. An improved process for the preparation of Dabigatran Etexilate mesylate and synthesis of its impurities. Pharma Chemica. Volume 10. Issue 4. Pages 127-148. Journal; Online Computer File. (2018).
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