Sapropterin CAS# 62989-33-7 / 69056-38-8 沙丙蝶呤
Sapropterin, also known as Tetrahydrobiopterin (BH4, THB, trade name Kuvan) or sapropterin (INN) is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative.
📌 参考资料/链接：
Lyudnikova, T. A.; Dashina, O. A.; Telegina, T. A.; Kritsky, M. S. Investigation of the photochemical properties of biopterin and its reduced forms. Applied Biochemistry and Microbiology. Volume 45. Issue 1. Pages 104-109. 2009.
Lyudnikova, T. A.; Dashina, O. A.; Telegina, T. A.; Kritsky, M. S. Investigation of the photochemical properties of biopterin and its reduced forms. Applied Biochemistry and Microbiology. Volume 45. Issue 1. Pages 104-109. 2009.
📄 详细内容
CAS No. 62989-33-7 / 69056-38-8 沙丙蝶呤Sapropterin synthetic routes
Lyudnikova, T. A.; Dashina, O. A.; Telegina, T. A.; Kritsky, M. S. Investigation of the photochemical properties of biopterin and its reduced forms. Applied Biochemistry and Microbiology. Volume 45. Issue 1. Pages 104-109. 2009.
产品链接: CAS No. 62989-33-7 / 69056-38-8 ››
Lyudnikova, T. A.; Dashina, O. A.; Telegina, T. A.; Kritsky, M. S. Investigation of the photochemical properties of biopterin and its reduced forms. Applied Biochemistry and Microbiology. Volume 45. Issue 1. Pages 104-109. 2009.
产品链接: CAS No. 62989-33-7 / 69056-38-8 ››