Ulipristal CAS# 159811-51-5 乌利司他
Ulipristal acetate, also known as CDB-2914, is a selective progesterone receptor modulator (SPRM) approved for contraception, and for uterine fibroid. As a SPRM, ulipristal acetate has partial agonistic as well as antagonistic effects on the progesterone receptor. It also binds to the glucocorticoid receptor, but is only a weak antiglucocorticoid relative to mifepristone, and has no relevant affinity to the estrogen, androgen and mineralocorticoid receptors.
📌 参考资料/链接：
Kim, Hyun K.; Rao, Pemmaraju Narasinha; Burdett, James E., Jr.; Acosta, Carmie Kirk. improved preparation of 17α-acetoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione and its intermediates. Assignee United States Dept. of Health and Human Services, USA. WO 9630390. (1996).
Kim, Hyun K.; Rao, Pemmaraju Narasinha; Burdett, James E., Jr.; Acosta, Carmie Kirk. improved preparation of 17α-acetoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione and its intermediates. Assignee United States Dept. of Health and Human Services, USA. WO 9630390. (1996).
📄 详细内容
CAS No. 159811-51-5 乌利司他Ulipristal synthetic routes
Kim, Hyun K.; Rao, Pemmaraju Narasinha; Burdett, James E., Jr.; Acosta, Carmie Kirk. improved preparation of 17α-acetoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione and its intermediates. Assignee United States Dept. of Health and Human Services, USA. WO 9630390. (1996).
产品链接: CAS No. 159811-51-5 ››
Kim, Hyun K.; Rao, Pemmaraju Narasinha; Burdett, James E., Jr.; Acosta, Carmie Kirk. improved preparation of 17α-acetoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione and its intermediates. Assignee United States Dept. of Health and Human Services, USA. WO 9630390. (1996).
产品链接: CAS No. 159811-51-5 ››