CAS: 700-87-8; 1-Isocyanato-2-Methoxybenzene

该化合物是一种有机化合物,其特征是附于甲氧基替代苯环的异丙氰酸盐功能组(-N=C=O),该化合物一般是无色的黄色液体,具有独特的气味,以其反应性而闻名,特别是在与酒精或氨反应时形成聚氨酯联系,使其在合成各种聚合物和药物中具有价值.甲基氧基组增强其在有机溶剂中的溶性,并能影响其再活性.2-甲基苯丙胺对湿度也很敏感,可导致水解,产生相应的矿和二氧化碳.在处理该化合物时,安全防范至关重要,因为异丁酸盐可以是刺激剂,对接触健康构成危险.建议适当储存在冷干的地方,同时使用个人防护设备,以减轻潜在危害.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号32315-10-9 三光气 | CAS号90-04-0 邻氨基苯甲醚 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号75-44-5 光气 | CAS号503-38-8 氯甲酸三氯甲酯 | CAS号83943-67-3 o-methoxybenzoy... | CAS号71-43-2 苯 | CAS号106212-55-9 2-(2-methoxyani... | CAS号100926-75-8 quinolin-6-yl N... | CAS号20220-77-3 Benzenamine,N,N... | CAS号29209-19-6 N-(2-Methoxyphe... | CAS号28788-16-1 Urea,N-hydroxy-... | CAS号1226-63-7 Urea,N,N'-bis(2... | CAS号76393-39-0 3-(4-ethylpheny... | CAS号76875-80-4 (2-Methoxypheny... | CAS号76947-68-7 1-(2-methoxyphe... | CAS号62774-58-7 1-amino-3-(2-me...

合成工艺路线路线简述

  • 合成目标产物 2-Methoxyphenyl Isocyanate 主要起始原料 Triphosgene And O-Anisidine
  • (文献来源)合成步骤主要原料 Triphosgene 和 O-Anisidine
邻甲氧基苯甲酰叠氮化物置于苯体系中,化学反应生成 2-甲氧基苯基异氰酸酯
参考文献:Stoermer,Chemische Berichte,1909,Vol. 42,P. 3133
标题:Stoermer,Chemische Berichte,1909,Vol. 42,P. 3133

海关参考信息

专利信息


专利号:WO-9700244-A1
优先权日:1995-06-19
标题 :Process for parallel synthesis of a non-peptide library
发明人:FRITZ JAMES E; KALDOR STEPHEN W
权利人:LILLY CO ELI; FRITZ JAMES E; KALDOR STEPHEN W
摘要:A process for the sequential preparation of a library of compounds having pharmaceutical usage. The process involves the sequential mixing of solution phase reagents, followed by scavenging of excess unreacted reagents with solid phase scavenging agents. The process is highly iterative and applicable for producing various ureas, thiureas, amides, carbonates and tertiary amines.

专利号:US-4578514-A
优先权日:1984-11-01
标题 :Synthesis of sulfilimines
发明人:GETMAN DANIEL P
权利人:MONSANTO CO
摘要:Processes are disclosed for preparation of N-aryl-S,S-dihydrocarbylsulfilimines by reaction of phenylisocyanate compounds with hydrocarbyl sulfoxides. The sulfilimines can be rearranged to ortho-thioalkylene anilines and the reactions can be employed in a route for converting nitrobenzene compounds to ortho-thioalkylene anilines, which are useful intermediates for preparation of herbicidal compounds.

专利号:US-2022281888-A1
优先权日:2019-09-25
标题:Bicyclic carboxylates as modulators of transporters and uses thereof
发明人:SANDANAYAKA VINCENT; GORECZNY GREGORY
权利人:NIROGY THERAPEUTICS INC
摘要:The present invention generally relates to the field of transporter modulators, e.g., monocarboxylate transporter inhibitors, and more particularly to new bicyclic enone carboxylate compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with monocarboxylate transporter activity such as in treating cancer and other neoplastic disorders, tissue and organ transplant rejection.

专利号:US-2009012242-A1
优先权日:2008-03-07
标题 :Synthesis of polyimides (pi) from poly-carbodiimides and dianhydrides by sequential self-repetitive reaction (ssrr)

专利号:US-4158672-A
优先权日:1976-01-26
标题 :Polyfluoroalkylthio alcohols, esters and useful compositions therefrom
发明人:DEAR ROBERT E A; BRACE NEAL O
权利人:CIBA GEIGY CORP
摘要:Polyfluoroalkylthio alcohols and esters thereof are disclosed with utility as intermediates for the synthesis of fluorochemicals with low free surface energies having oil and water repellent properties. The novel alcohols and esters are obtained by a free radical catalyzed addition of polyfluoroalkylthiols to acetylenic alcohols or esters thereof. The alcohols are employed in preparation of fluorine containing polyurethanes which are useful as finishes to provide oil and water repellency to textiles and as additives to plastics to provide mold release and other desirable properties.

专利号:US-4775757-A
优先权日:1986-09-22
标题:Thienopyridines useful as cardiovascular agents
发明人:KANOJIA RAMESH M; MCNALLY JAMES J; PRESS JEFFERY B
权利人:ORTHO PHARMA CORP
摘要:The synthesis of thienopyridine derivatives is described. The novel thienopyridine derivatives are cardiotonic agents and renal vasodilating agents. The compounds are useful as cardiovascular agents.
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合成参考文献


摘要:Braverman, S.; Cherkinsky, M., Science of Synthesis Knowledge Updates, (2014) 3, 296.
摘要:Aubert, C.; Malacria, M.; Ollivier, C., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 199.
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