专利号:WO-9700244-A1 优先权日:1995-06-19 标题 :Process for parallel synthesis of a non-peptide library 发明人:FRITZ JAMES E; KALDOR STEPHEN W 权利人:LILLY CO ELI; FRITZ JAMES E; KALDOR STEPHEN W 摘要:A process for the sequential preparation of a library of compounds having pharmaceutical usage. The process involves the sequential mixing of solution phase reagents, followed by scavenging of excess unreacted reagents with solid phase scavenging agents. The process is highly iterative and applicable for producing various ureas, thiureas, amides, carbonates and tertiary amines.
专利号:US-4578514-A 优先权日:1984-11-01 标题 :Synthesis of sulfilimines 发明人:GETMAN DANIEL P 权利人:MONSANTO CO 摘要:Processes are disclosed for preparation of N-aryl-S,S-dihydrocarbylsulfilimines by reaction of phenylisocyanate compounds with hydrocarbyl sulfoxides. The sulfilimines can be rearranged to ortho-thioalkylene anilines and the reactions can be employed in a route for converting nitrobenzene compounds to ortho-thioalkylene anilines, which are useful intermediates for preparation of herbicidal compounds.
专利号:US-2022281888-A1 优先权日:2019-09-25 标题:Bicyclic carboxylates as modulators of transporters and uses thereof 发明人:SANDANAYAKA VINCENT; GORECZNY GREGORY 权利人:NIROGY THERAPEUTICS INC 摘要:The present invention generally relates to the field of transporter modulators, e.g., monocarboxylate transporter inhibitors, and more particularly to new bicyclic enone carboxylate compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with monocarboxylate transporter activity such as in treating cancer and other neoplastic disorders, tissue and organ transplant rejection.
专利号:US-2009012242-A1 优先权日:2008-03-07 标题 :Synthesis of polyimides (pi) from poly-carbodiimides and dianhydrides by sequential self-repetitive reaction (ssrr)
专利号:US-4158672-A 优先权日:1976-01-26 标题 :Polyfluoroalkylthio alcohols, esters and useful compositions therefrom 发明人:DEAR ROBERT E A; BRACE NEAL O 权利人:CIBA GEIGY CORP 摘要:Polyfluoroalkylthio alcohols and esters thereof are disclosed with utility as intermediates for the synthesis of fluorochemicals with low free surface energies having oil and water repellent properties. The novel alcohols and esters are obtained by a free radical catalyzed addition of polyfluoroalkylthiols to acetylenic alcohols or esters thereof. The alcohols are employed in preparation of fluorine containing polyurethanes which are useful as finishes to provide oil and water repellency to textiles and as additives to plastics to provide mold release and other desirable properties.
专利号:US-4775757-A 优先权日:1986-09-22 标题:Thienopyridines useful as cardiovascular agents 发明人:KANOJIA RAMESH M; MCNALLY JAMES J; PRESS JEFFERY B 权利人:ORTHO PHARMA CORP 摘要:The synthesis of thienopyridine derivatives is described. The novel thienopyridine derivatives are cardiotonic agents and renal vasodilating agents. The compounds are useful as cardiovascular agents.