CAS: 529-55-5; (S)-5-Hydroxy-2-(4-Hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Chroman-4-One

上下游产品

naringin formic acid cyclohexanol naringenin 7-O-(6-O-((E)-p-coumaroyl)-β-D-glucopyranoside)prunin 6''-O-acetate prunin 6''-O-butyrate prunin 6''-O-decanoate prunin 6''-O-laurate

📜柚皮苷置于aspergillus Niger Naringenase体系中,用 水 作为反应溶剂,化学反应生成 柚(苷)配基-7-O-葡糖苷
参考文献:Thermal Inactivation And Product Inhibition Ofaspergillus Terreuscect 2663 α-L-Rhamnosidase And Their Role On Hydrolysis Of Naringin Solutions
标题:Thermal Inactivation And Product Inhibition Ofaspergillus Terreuscect 2663 α-L-Rhamnosidase And Their Role On Hydrolysis Of Naringin Solutions
摘要:使用底物对硝基苯α-L-鼠李糖苷在 50oc 和 70oc 之间研究了赤霉菌α-鼠李糖苷酶热失活的动力学.在 60oc 以下,纯化酶的失活是完全可逆的,但粗酶或部分纯化酶样品显示出部分可逆性.产品鼠李糖,底物柚皮苷和其他添加剂的存在降低了可逆性失活,在某些情况下,60oc 时仍能保持酶的全部活性.研究人员提出了灭活过程的机理,从而使实验结果得以重现.产品鼠李糖(抑制常数 2.1 Mm)和杨梅素(2.6 Mm)竞争性地抑制了酶反应.过饱和柚皮苷溶液的最大水解温度为 60°C,酶未失活.在 1%的柚皮苷溶液中,柚皮苷的水解度达到 99%,但当黄酮类化合物的初始浓度为 10%时,由于产物抑制,柚皮苷的水解度仅为 40%.实验结果与基于综合 Michaelis-Menten 的方程相吻合,包括产物的竞争性抑制作用,结果令人满意.
DOI:10.1271/bbb.66.1442

专利信息

专利号:US-8143308-B2
优先权日:2005-04-28
标题 :Synthesis of oligo/poly(catechins) and methods of use
发明人：BRUNO FERDINANDO F; KUMAR JAYANT; NAGARAJAN SUBHALAKSHMI; BRAUNHUT SUSAN J; NAGARAJAN RAMASWAMY; SAMUELSON LYNNE A; MCINTOSH DONNA; FOLEY KLAUDIA
权利人:BRUNO FERDINANDO F; KUMAR JAYANT; NAGARAJAN SUBHALAKSHMI; BRAUNHUT SUSAN J; NAGARAJAN RAMASWAMY; SAMUELSON LYNNE A; MCINTOSH DONNA; FOLEY KLAUDIA; UNIV MASSACHUSETTS LOWELL; US ARMY
摘要:A method for synthesizing a biocompatible, water-soluble oligo/polyflavanoid, includes polymerizing an optionally substituted flavanoid with a polymerization agent in the presence of a biocompatible polymerization solubilizer, thereby producing the biocompatible, soluble oligo/polyflavanoid. Also included is a biocompatible, soluble, oligo/polyflavanoid or a pharmaceutically acceptable salt, solvate, or complex thereof. Also included are methods of treating a subject for cancer, cardiac damage, viral infection, and obesity.

专利号:CN-110184247-B
优先权日:2019-05-09
标 题:Melatonin synthesis gene MsASMT in alfalfa and its application in regulating the synthesis of melatonin and flavonoids in plants

专利号:US-2009170928-A1
优先权日:2005-04-28
标题:Synthesis of oligo/poly(catechins) and methods of use

专利号:WO-2006116532-A2
优先权日:2005-04-28
标题:Synthesis of oligo/poly(catechins) and methods of use

专利号:CN-119331888-A
优先权日:2024-10-10
标题:Polygonatum cyrtonema PcF3H gene and application thereof in promotion of synthesis of dihydroflavonoid compounds and catalysis of naringenin hydroxylation

专利号:US-8350125-B2
优先权日:2003-12-17
标 题 :Method for producing yellow flower by controlling flavonoid synthetic pathway
发明人：TANAKA YOSHIKAZU; ONO EIICHIRO; NAKAMURA NORIKO; MIZUTANI MASAKO
权利人:SUNTORY HOLDINGS LTD; TANAKA YOSHIKAZU; ONO EIICHIRO; NAKAMURA NORIKO; MIZUTANI MASAKO
摘要:There is provided a gene coding for the amino acid sequence listed as SEQ ID NO: 2 or SEQ ID NO: 70, for example. Co-expression of the 4′CGT gene and AS gene in a plant lacking natural aurone synthesis ability is carried out to successfully accumulate aurones and alter the flower color to have a yellow tint. In addition to the expression of both genes, the flavonoid pigment synthesis pathway of the host plant itself is inhibited to obtain flowers with a more defined yellow color.