CAS: 524-30-1; 7-Hydroxy-6-Methoxy-8-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-2H-Chromen-2-One
该化合物是一种化学化合物,被归类为氟氯素,具体地说是氟氯素的胶片边,主要来自灰树(genus Fraxinus),以其潜在的生物活动著称;Fraxin具有抗氧化剂特性,可能有助于保护细胞免受氧化性压力;此外,还研究其抗炎和抗微生物效应,使其在各个领域,包括药理学和天然产品研究中引起兴趣;该化合物通常以白色到黄色的晶状粉的形式出现,在水和酒精中溶解,便于从植物来源提取;其结构包括氟芳骨,这是许多氟芳素的特征,它可能与各种生物途径相互作用,可能影响健康结果;与许多天然化合物一样,正在进一步研究如何充分阐明其行动和治疗潜力机制.
- 英文名称7-Hydroxy-6-Methoxy-8-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-2H-Chromen-2-One
- 中文名称秦皮苷
- IUPAC名称7-hydroxy-6-methoxy-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one
- 其它别名7-Hydroxy-6-Methoxy-8-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-2H-Chromen-2-One; Inchi=1/c16H18O10/c1-23-7-4-6-2-3-9(18)25-14(6)15(11(7)20)26-16-13(22)12(21)10(19)8(5-17)24-16/h2-4,8,10,12-13,16-17,19-22H,5H2,1H3
- CAS编号524-30-1
- MFCD编号:MFCD00010093
- EINECS号:208-355-5
- FDA UNII编号:V7M270Y072
- 分子式:C16H18O10分子量:370.31
- 产品CID: 1513688
- 产品分类生物化工 → 中草药成分
物理性质
- 熔点205-208 °C
- 沸点722.2±60.0 °C at 760 mmHg
- 闪点267.1±26.4 °C
- 密度1.6±0.1 g/cm3
- pKa:6.99±0.20(预测)
- PSA:159.05
- LogP:-1.93
- 折射率1.664
- 蒸汽压0.0±2.5 mmHg at 25°C
- 溶解性DMSO: 250 mg/mL (675.11 Mm; Need Ultrasonic)
- 外观形态白色固体
- 储存条件密封, 常温干燥保存
- 产品应用该化合物用作眼科眼滴治疗眼病;作为生物化学试剂和高纯度化妆添加剂;通过在兔子和风湿病病人中推广尿酸排泄物来显示尿性活动;抑制因丁胺而导致的毛虫渗透;抑制大鼠中的CARANGEENAN-,DEXTRAN-,甲状体-和甲胺诱发的爪状腺.
MSDS等安全信息
上下游产品
CAS号574-84-5 秦皮素合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2023156270-A1
优先权日:2022-02-18
标题:Coumarin synthesis and uses thereof
发明人：CONRATH UWE; LANGENBACH CASPAR; BEYER SEBASTIAN FELIX; SCHWINGES PATRICK; SCHULTHEISS HOLGER; BEESLEY ALEXANDER; LINKE CEDRIC
权利人:BASF SE; RWTH AACHEN
摘要:The present invention relates to genes, materials and methods for coumarin synthesis and the application thereof for improving plant health, preferably against infection by phythopathogenic microorganisms, and/or for improving plant health against coumarin-induced adverse effects on plant health. Furthermore, the invention pertains to methods and uses of such genes and mate- rials for creating correspondingly beneficial plant cells, plant parts and whole plants, and relates to products obtained from such plants or plant parts.
专利号:US-2025231101-A1
优先权日:2024-01-11
标 题 :Validation of natural matrices for therapeutic use on humans, animals and plants on bio-physical bases as an alternative to validation through chemically definable substances derived from said matrices by isolation and/or synthesis processes and also as an alternative to products comprising natural matrices validated on the basis of their traditional use
发明人：MERCATI VALENTINO; LUCCI JACOPO
权利人:BIOS THERAPY PHYSIOLOGICAL SYSTEMS FOR HEALTH S P A
摘要:The present invention relates to a new method for assessing acceptability ranges or cut-offs for the compliance validation of batches of products comprising or consisting of one or more natural matrix, wherein said products have an ascertained therapeutic or beneficial effect. The invention also relates to a new process for the compliance validation of one or more batches of said products.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Yasuda T, Fukui M, Nakazawa T, Hoshikawa A, Ohsawa K. Metabolic fate of fraxin administered orally to rats. J Nat Prod. 2006 May;69(5):755-7.
合成参考文献
参考文献:10.1007/s10753-019-01052-8
摘要:Ma X, Liu X, Feng J, Zhang D, Huang L, Li D, Yin L, Li L, Wang XZ. Fraxin Alleviates LPS-Induced ARDS by Downregulating Inflammatory Responses and Oxidative Damages and Reducing Pulmonary Vascular Permeability. Inflammation. 2019 Oct;42(5):1901–12. doi: 10.1007/s10753-019-01052-8.
参考文献:10.3389/fbioe.2021.662655
摘要:He J, Liu C, Du M, Zhou X, Hu Z, Lei A, Wang J. Metabolic Responses of a Model Green Microalga Euglena gracilis to Different Environmental Stresses. Front Bioeng Biotechnol. 2021;9():662655.
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