CAS: 474-77-1; Epicholesterol

该化合物是生物膜结构和功能所不可或缺的一种无胆固醇分子,是类固醇激素,丁酸和维生素D合成的前体. (3β)配置表示C-3位置的氢氧基群体定向,这是其生化活动的关键特征.该化合物由于纯度和稳定性高,广泛用于研究,制药配方,并用作分析化学的标准.它在脂质代谢和细胞信号方面的作用使它成为生物化学,医药和营养研究的宝贵参考材料.适当的处理和储存确保其在实验应用中的完整.

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313-04-2 474-67-9 2862-58-0

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    CAS号601-57-0 4-胆甾烯-3-酮 | CAS号566-88-1 5alpha-Cholesta... | CAS号601-53-6 (5β)-Cholestan-3-one

    合成工艺路线路线简述

      📜Cholesterol置于aluminum Isopropoxide,苯体系中,化学反应生成 表胆甾醇
      参考文献:Barnett Et Al.,Journal Of The Chemical Society,1940,P. 1390,1392
      标题:Barnett Et Al.,Journal Of The Chemical Society,1940,P. 1390,1392

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      专利信息


      专利号:WO-2025217610-A1
      优先权日:2024-04-12
      标题:Systems and methods for enzymatic oligonucleotide synthesis
      发明人:ENTWISTLE DAVID; GAUNTLETT DEREK; MILLER MICHAEL; REEVES RYAN; WATTS DAVID
      权利人:CODEXIS INC
      摘要:The present invention provides for methods and systems for template-free synthesis of an oligonucleotide, and methods of using the systems as disclosed herein for template-free synthesis of an oligonucleotide.

      专利号:US-2025145659-A1
      优先权日:2022-02-11
      标题 :Synthesis of cholesterol form bisnoralcohol
      发明人:DATLA ANUPAMA; NAGRE PRASHANT; TAMORE JAGDISH; WADHAVANE SACHIN GOVIND; SHIRSATH AMOL; GAONKAR GAJANAN SUBHASH
      权利人:FERMENTA BIOTECH LTD
      摘要:The present invention discloses a short, cost effective process for preparation of cholesterol from bisnoralcohol (BA).

      专利号:US-7018633-B2
      优先权日:2000-02-16
      标题 :Selective destruction of cells infected with human immunodeficiency virus
      发明人:KEENER WILLIAM K; WARD THOMAS E
      权利人:BATTELLE ENERGY ALLIANCE LLC
      摘要:Compositions and methods for selectively killing a cell containing a viral protease are disclosed. The composition is a varient of a protein synthesis inactivating toxin wherein a viral protease cleavage site is interposed between the A and B chains. The variant of the type II ribosome-inactivating protein is activated by digestion of the viral protease cleavage site by the specific viral protease. The activated ribosome-inactivating protein then kills the cell by inactivating cellular ribosomes. A preferred embodiment of the invention is specific for human immunodeficiency virus (HIV) and uses ricin as the ribosome-inactivating protein. In another preferred embodiment of the invention, the variant of the ribosome-inactivating protein is modified by attachment of one or more hydrophobic agents. The hydrophobic agent facilitates entry of the variant of the ribosome-inactivating protein into cells and can lead to incorporation of the ribosome-inactivating protein into viral particles. Still another preferred embodiment of the invention includes a targeting moiety attached to the variants of the ribosome-inactivating protein to target the agent to HIV infectable cells.

      专利号:WO-2023152768-A1
      优先权日:2022-02-11
      标 题 :Synthesis of cholesterol form bisnoralcohol

      专利号:EP-4452409-A1
      优先权日:2022-02-11
      标 题 :Synthesis of cholesterol form bisnoralcohol

      专利号:WO-2010071772-A2
      优先权日:2008-12-15
      标题:Synthesis of 3b-amino-5-cholestene and related 3b-halides involving i-steroid and retro-i-steroid rearrangements

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      ✅ COA系统入驻 | 共享模式

      合成参考文献


      参考文献:10.1007/s00253-008-1526-y
      摘要:Doukyu N, Shibata K, Ogino H, Sagermann M. Purification and characterization of Chromobacterium sp. DS-1 cholesterol oxidase with thermal, organic solvent, and detergent tolerance. Appl Microbiol Biotechnol. 2008 Aug;80(1):59–70. doi: 10.1007/s00253-008-1526-y.
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