专利号:US-10005720-B2 优先权日:2013-04-05 标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same 发明人:SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L 权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL 摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.
专利号:US-2018370905-A1 优先权日:2013-04-05 标题:Compounds Useful for the Treatment of Metabolic Disorders and Synthesis of the Same
专利号:US-2016046560-A1 优先权日:2013-04-05 标题 :Compounds useful for the treatment of metabolic disorders and synthesis of the same
专利号:US-8034960-B2 优先权日:2004-08-19 标 题:Process for the synthesis C-2, C-3 substituted N-alkylated indoles useful as cPLA2 inhibitors 发明人:MICHALAK RONALD S; LEVENT MAHMUT; VYVERBERG FREDERICK J; BOYAJIAN ARA R; RAVEENDRANATH PANOLIL; CANTIN MICHEL; STOCKTON ALAN; WINKLEY MICHAEL W; GHOSH MOUSUMI; DEHNHARDT CHRISTOPH; GUINOSSO CHARLES 权利人:PFIZER 摘要:The present invention provides a compound of formula 1: n nwherein R 1 is CF 3 , R 2 is H′ R 3 is H.
专利号:US-2009306428-A1 优先权日:2004-08-19 标 题 :Process for the Synthesis of C-2, C-3 Substituted N-Alkylated Indoles Useful as cPLA2 Inhibitors
专利号:US-7842837-B2 优先权日:2004-08-19 标 题 :Process for the synthesis of C-2, C-3 substituted N-alkylated indoles useful as cPLA2 inhibitors