CAS: 4068-78-4; Methyl 5-Chloro-2-Hydroxybenzoate

上下游产品

CAS号321-14-2 5-氯代水杨酸 | CAS号67-56-1 甲醇 | CAS号119-36-8 水杨酸甲酯 | CAS号75-36-5 乙酰氯 | CAS号74-88-4 碘甲烷 | CAS号1126-46-1 甲基-4-氯苯甲酸甲酯 | CAS号69-72-7 水杨酸 | CAS号16487-46-0 methyl N,N-dich... | CAS号76-06-2 氯化苦 | CAS号3261-05-0 5-氯苯并呋喃-3(2H)-酮 | CAS号439117-38-1 5-氯-2-氰基苯甲酸甲酯 | CAS号141762-02-9 3,4-二氢-4-甲基-3-氧... | CAS号5043-81-2 3-氨基-5-氯-2-羟基苯甲酸甲酯 | CAS号5022-48-0 5-氯-2-羟基苯甲酰肼 | CAS号197504-51-1 6-氯-4-羟基-3-甲基-2... | CAS号20324-50-9 5-氯-2-巯基苯甲酸 | CAS号189308-64-3 5-chloro-2,2-di... | CAS号5330-38-1 5-氯-2-羟基苯甲醇 | CAS号7120-43-6 5-氯水杨酰胺

水杨酸甲酯 以 氯仿 作为反应溶剂,以152 G (81.5%)的收率获得产物5-氯-2-羟基苯甲酸甲酯
参考文献:Halo-Containing 3-Methylflavone-8-Carboxylic Acid Derivatives
标题:Halo-Containing 3-Methylflavone-8-Carboxylic Acid Derivatives
摘要:这项发明涉及由式(1)表示的3-甲基黄酮-8-羧酸衍生物 ##str1## 其中r代表氢原子,较低的烷基基团或基团 ##str2## (其中r.Sup.1和r.Sup.2代表较低的烷基基团或r.Sup.1和r.Sup.2,当与它们连接的氮原子一起时,可以形成具有或不具有介入杂原子的杂环环,N为1至4的整数),X代表卤原子,这些衍生物可用作中间体.这项发明还涉及制备这些衍生物的方法.

专利信息

专利号:US-H1406-H
优先权日:1993-04-30
标题:Process for preparing dibenzofurans via catalytic heteroannulation
发明人：POWERS MATTHEW R
权利人:RHONE POULENC RORER PHARMA
摘要:The present invention is directed to the synthesis of 2-chloro-cis-[5a(S)-9a(S)-(5a,6,7,8,9,9a-hexahydro)]dibenzofuran-4-carboxylic acid by a stereospecific catalytic heteroannulation synthesis free of undesirable 8-chloro-2,6-methano-2H-3,4,5,6-tetrahydro-1-benzoxocin-10-carboxylic.

专利号:US-5278323-A
优先权日:1993-04-30
标 题 :Process for preparing chiral dibenzofurans via intramolecular heck reaction
发明人：POWERS MATTHEW R
权利人:RHONE POULENC RORER PHARMA
摘要:The present invention is directed to the synthesis of 2-chloro-cis-[5a(S)-9a(S)-(5a,6,7,8,9,9a-hexahydro)]dibenzofuran-4-carboxylic acid by an intramolecular Heck stereospecific synthesis substantially free of undesirable 8-chloro-2,6-methano-2H-3,4,5,6-tetrahydro-1-benzoxocin-10-carboxylic.

专利号:RU-2411234-C2
优先权日:2004-12-16
标题 :Method for synthesis of n-substituted salicylamides

专利号:US-2012053165-A1
优先权日:2009-03-03
标 题:Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators
发明人：ALLEN MARTIN PATRICK; AM ENDE CHRISTOPHER WILLIAM; BRODNEY MICHAEL AARON; DOUNAY AMY BETH; JOHNSON DOUGLAS SCOTT; PETTERSSON MARTIN YOUNGJIN; SCHWARTZ JACOB BRADLEY; TRAN TUAN PHONG
权利人:ALLEN MARTIN PATRICK; AM ENDE CHRISTOPHER WILLIAM; BRODNEY MICHAEL AARON; DOUNAY AMY BETH; JOHNSON DOUGLAS SCOTT; PETTERSSON MARTIN YOUNGJIN; SCHWARTZ JACOB BRADLEY; TRAN TUAN PHONG; PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-9067934-B2
优先权日:2011-03-31
标题 :Bicyclic pyridinones
发明人：PETTERSSON MARTIN YOUNGJIN; JOHNSON DOUGLAS SCOTT; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; AM ENDE CHRISTOPHER WILLIAM; FISH BENJAMIN ADAM; GREEN MICHAEL ERIC; MULLINS PATRICK BRADLEY; STIFF CORY MICHAEL; TRAN TUAN PHONG; NAVARATNAM THAYALAN
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n nas defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-2012202787-A1
优先权日:2009-10-20
标 题:Novel Heteroaryl Imidazoles And Heteroaryl Triazoles As Gamma-Secretase Modulators
发明人：AM ENDE CHRISTOPHER WILLIAM; JOHNSON DOUGLAS SCOTT; PETTERSSON MARTIN YOUNGJIN; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN
权利人:AM ENDE CHRISTOPHER WILLIAM; JOHNSON DOUGLAS SCOTT; PETTERSSON MARTIN YOUNGJIN; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I; n n n n n n n n n n as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.