CAS: 353-54-8; Tribromofluoromethane

该化合物是一种卤化碳氢化合物,在灭火和化学合成中具有显著应用,其高密度和高热稳定性使该物质成为灭火剂,特别是在传统抑制剂不合适的专门环境中.该化合物的溴含量通过中断燃烧链反应而助长其阻燃性能.此外,氟三溴甲烷是有机合成的试剂,其溴原子可促进选择性卤化反应.它与普通材料的低再活动可确保工业系统的兼容性.适当处理由于其对环境和健康的潜在影响,要求遵守储存和处置的安全议定书,因此其适当处理至关重要.

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欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号558-13-4 四溴化碳 | CAS号7783-56-4 三氟化锑 | CAS号7787-71-5 三氟化溴 | CAS号81962-38-1 [dibromo(fluoro... | CAS号676353-70-1 iodide pentafluoride | CAS号75-69-4 三氯氟甲烷 | CAS号358-23-6 三氟甲磺酸酐 | CAS号74501-99-8 fluoroformyl tr... | CAS号7726-95-6 溴素 | CAS号753-56-0 carbonyl bromid... | CAS号4539-11-1 bromofluor°Carbene | CAS号41895-46-9 dibromo(fluoro)... | CAS号7446-09-5 二氧化硫 | CAS号197451-56-2 (1,3,3-tribromo... | CAS号202526-04-3 1,1,3-tribromo-...

合成工艺路线路线简述

    📜四溴化碳置于溴,三氟化锑体系中,化学反应生成氟三溴甲烷
    参考文献:Rathsburg,Chemische Berichte,1918,Vol. 51,P. 672
    标题:Rathsburg,Chemische Berichte,1918,Vol. 51,P. 672

    海关参考信息

    专利信息


    专利号:US-7572778-B2
    优先权日:2003-07-18
    标题 :Fluorocombretastatin and derivatives thereof
    发明人:GIANNINI GIUSEPPE; ALLOATTI DOMENICO; MARCELLINI MARCELLA; MARZI MAURO; RICCIONI TERESA; TINTI MARIA ORNELLA
    权利人:SIGMA TAU IND FARMACEUTI
    摘要:The present invention is related to new derivatives of Combretastatin, of Formula n nobtained by total synthesis. The strategy developed for each of the compounds is to i) replace a halogen (i.e. fluorine atom) to hydrogen on olefinic bound; ii) replace an aromatic ring in a natural product with an amino-aromatic ring. Said compounds recognize and bind the tubulin site: are useful for treating pathological states which arise from or are exacerbated by cell proliferation—as anticancer and/or antiangiogenic activity, in a mammal—to pharmaceutical compositions comprising these compounds.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Aitken, R. A.; Boubalouta, Y., Science of Synthesis Knowledge Updates, (2013) 4, 129.
    摘要:Podlech, J., Science of Synthesis Knowledge Updates, (2019) 1, 380.
    摘要:Huy, P.; Czekelius, C., Science of Synthesis Knowledge Updates, (2019) 2, 120.
    摘要:Cormier, M.; Goddard, J.-P., Science of Synthesis, (2020) , 157.
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