CAS: 3182-95-4; (S)-2-Amino-3-Phenylpropan-1-Ol

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上下游产品

CAS号63-91-2 L-苯丙氨酸 | CAS号7524-50-7 L-苯丙氨酸甲酯盐酸盐 | CAS号2577-90-4 (S)-2-氨基-3-苯基丙酸甲酯 | CAS号6372-14-1 Cbz-L-苯丙氨醇 | CAS号3182-93-2 L-苯丙氨酸乙酯盐酸盐 | CAS号59830-60-3 N-苄氧羰基-L-苯丙氨醛 | CAS号150-30-1 DL-苯丙氨酸 | CAS号2935-35-5 (|S|)-(+)-α-苯甘氨酸 | CAS号129397-83-7 (s)-N-FM°C基苯丙氨醇 | CAS号141403-49-8 (S)-2-叔丁氧酰胺基苯丙醇... | CAS号223600-53-1 1-[(2S)-1-hydro... | CAS号300-57-2 烯丙基苯 | CAS号93-54-9 1-苯基-1-丙醇 | CAS号1334326-63-4 5-benzyl-3-meth... | CAS号29802-26-4 (2S)-N1,N1-Dime... | CAS号82495-70-3 (S)-(-)-N-[1-(羟... | CAS号90719-32-7 |S|-4-苄基-2-恶唑烷酮 | CAS号2448-45-5 N-CBZ-D-苯丙氨酸 | CAS号2323-36-6 1-[4-[2-[(4-chl...

L-苯丙氨酸乙酯盐酸盐置于sodium Tetrahydroborate体系中,用 乙醇,水 作为反应溶剂,化学反应 4.5H,以72%的收率获得产物l-苯丙氨醇
参考文献:通过分子内亚氨基 Diels-Alder 反应非对映选择性合成反式稠合吡咯并 [3,4-B] 喹啉
标题:通过分子内亚氨基 Diels-Alder 反应非对映选择性合成反式稠合吡咯并 [3,4-B] 喹啉
摘要:摘要 通过芳香胺衍生的醛亚胺与 (S)-2-(N-(3-Methylbut-) 分子内环化反应合成了一系列 1Ar,2S,4As-六氢吡咯并[3,4-B]喹啉. 2-烯基)-N-甲苯磺酰氨基)-3-甲基丙醛/(S)-2-(N-(3-甲基丁-2-烯基)-N-甲苯磺酰氨基)-3-苯基丙醛在乙腈中用 Incl3 作为催化剂,在在温和的条件下,产量高,持续时间短.图形概要
DOI:10.1080/00397911.2011.572218

专利信息

专利号:US-7323575-B2
优先权日:2003-04-09
标题:Process for the synthesis of (2S)-indoline-2-carboxylic acid
发明人：SOUVIE JEAN-CLAUDE; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): n nApplication in the synthesis of perindopril and its pharmaceutically acceptable salts.

专利号:US-10040752-B2
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
发明人：MKRTCHYAN GNEL; YAO QINGWEI
权利人:CODY LABORATORIES INC
摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

专利号:US-4014895-A
优先权日:1972-06-22
标 题:Method for synthesis of optically active thiolactones
发明人：AOKI YASUHIKO; SUZUKI HIROYUKI; AKIYAMA HISAO; OKANO SHIGERU
权利人:SUMITOMO CHEMICAL CO
摘要:A new method for the production of intermediates in the synthesis of an optically active biotin, which comprises reacting a dicarboxylic acid of the formula: ##SPC1## n Or its reactive derivative with an optically active primary amine, reducing the resulting trione with a metal hydride, hydrolyzing the resultant amide-alcohol and treating the thus produced lactone with a thiolactonating agent to give a thiolactone of the formula: ##SPC2## n , the said trione and amide-alcohol being respectively novel and representable by the formulae: ##SPC3##

专利号:US-5554788-A
优先权日:1992-10-01
标 题 :Process for the stereoselective synthesis of 3-substituted 2-thiomethylpropionic acids
发明人：HOLLA WOLFGANG; KAMMERMEIER BERNHARD; BECK GERHARD
权利人:HOECHST AG
摘要:PCT No. PCT/EP93/02673 Sec. 371 Date May 15, 1995 Sec. 102(e) Date May 15, 1995 PCT Filed Sep. 30, 1993 PCT Pub. No. WO94/00789 PCT Pub. Date Apr. 14, 1994Process for the stereoselective synthesis of 3-substituted 2-thiomethylpropionic acids Compounds of the formula I I in which R1 and R2 are as defined can be prepared stereoselectively by reaction of acrylic acid or derivatives thereof or propionic acid or derivatives thereof with a chiral auxiliary, reaction with a mercaptan, stereoselective alkylation and subsequent hydrolysis and oxidation.

专利号:US-7189864-B2
优先权日:1990-11-19
标 题:Method of preparing intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P
权利人:SEARLE & CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde.

专利号:US-2008287407-A1
优先权日:2003-12-10
标题 :Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use
发明人：GARVEY DAVID S; FANG XINQIN; KHANAPURE SUBHASH P; RANATUNGA RAMANI R; WEY SHIOW-JYI
权利人:NITROMED INC
摘要:The invention describes novel nitrosated and/or nitrosylated pyruvate compounds and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated and/or nitrosylated pyruvate compound, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one pyruvate compound and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one pyruvate compound, that is optionally nitrosated and/or nitrosylated, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for treating diseases resulting from oxidative stress, diabetes, reperfusion injury following ischemia, preservation of tissues, organs, organ parts and/or limbs.