CAS: 200132-16-7; (S)-Perfluorophenyl 2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)-5-(3-((2,2,4,6,7-Pentamethyl-2,3-Dihydrobenzofuran-5-yl)Sulfonyl)Guanidino)Pentanoate
该化合物是一种常见用于peptide合成的化学化合物,特别是在有机化学和生物化学领域.该产品具有受保护的残留物,其中Fmoc(9-氟甲基苯丙基碳基)组群作为氨基氨基组的一个临时保护组群,允许在peptide组装过程中有选择性地作出反应.Pbf(2,2,4,4,6,7,7-五甲基二氢苯丙胺-5-硫基)系组群是另一个保护性学会,它保护了丙酰胺群,在合成过程中加强了该化合物的稳定性和再活动.OPfp(五溴二苯醚)的敏感性作用作用作为一个留居组,促进与其他氨基酸或丙酸碎片的混合反应.该化合物通常用于固态聚苯乙烯合成(SPSPS),其保护组可以有选择地去除以产生所需的peptedine产品.总体而言,Fmoco-Arg(Pbff)-OPpppt的稳定性,再活性和实用性,同时保持复合合成的合成的稳定性,并保持合成的特性.
- 英文名称(S)-Perfluorophenyl 2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)-5-(3-((2,2,4,6,7-Pentamethyl-2,3-Dihydrobenzofuran-5-yl)Sulfonyl)Guanidino)Pentanoate
- 中文名称N-α-FMOC-N-GAMMA-(2,2,4,6,7-五甲基二氢苯并呋喃-5-磺酰基)-L-精氨酸五氟苯酯
- IUPAC名称perfluorophenyl N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-Nw-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)-L-argininate
- CAS编号200132-16-7
- MFCD编号:MFCD00237040
- EINECS号:685-319-9
- 分子式:C40H39F5N4O7S分子量:814.83
- 产品CID: 1017304
- 产品分类生物化工 → 氨基酸及其衍生物 → 精氨酸类衍生物
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报合成工艺路线路线简述
专利信息
专利号:US-2017029467-A1
优先权日:2015-07-30
标 题:Method of producing bivalirudin
发明人：ZHANG GUOQING; ZHANG RUOPING; BAI JUNCAI
权利人:AMBIOPHARM INC
摘要:The present disclosure provides a method of producing bivalirudin using a peptide fragment or peptide fragments on solid phase peptide synthesis that minimizes, or eliminates, the production of bivalirudin molecules having too few or too many glycine residues.
专利号:CN-102816208-A
优先权日:2011-06-10
标 题:A kind of liquid phase synthesis method of bivalirudin
专利号:CN-102816208-B
优先权日:2011-06-10
标题 :A kind of liquid-phase synthesis process of bivalirudin
专利号:CN-104558162-A
优先权日:2013-10-23
标题:The solid-phase synthesis method of bivalirudin intermediate
专利号:CN-104558161-B
优先权日:2013-10-23
标题:The solid phase synthesis process of Angiomax intermediate
专利号:CN-104558162-B
优先权日:2013-10-23
标 题:The solid phase synthesis process of Angiomax intermediate
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Synthesis Of Bacterial Urease Flap Region Peptide Equivalents And Detection Of Rheumatoid Arthritis Antibodies Using Two Methods作者:Iwona Konieczna,Beata Kolesińska,Joanna Gleńska-Olender,Grzegorz Czerwonka,Inga Relich,Justyna Frączyk,Zbigniew J. Kamiński,Wiesław Kaca |发布日期:2020.3
摘要:Rheumatoid Arthritis (Ra) Is An Autoimmune Inflammatory Disease That Leads To Cartilage Damage, Joint Destruction And Bone Erosions. Serological Analysis Is One Of The Most Important Tools For Diagnosis Of Ra. The Aims Of Studies Were The Synthesis Of An Amino-Acid Library Of Epitope Chhldksikedvqfadsri Corresponding To The Flap Region Of H. Pylori Urease And Investigation Recognition By Serum Antibodies
合成参考文献
参考文献:10.1385/1-59259-666-5:443
摘要:Lo BKC, Reineke U. Antibody Epitope Mapping Using Arrays of Synthetic Peptides. 2003 Dec 05. In: Antibody Engineering. : Humana Press; 2003 Dec 05.
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