专利号:US-7662401-B2 优先权日:2002-04-08 标 题 :Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase 发明人:MAHE YANN; MEYBECK ALAIN 权利人:OREAL 摘要:The present invention relates to the cosmetic or pharmaceutical use of an extract of a nonfruiting nonphotosynthetic filamentous bacterium in a composition containing a cosmetically or pharmaceutically acceptable medium, as an agent increasing the endogenous synthesis of superoxide dismutase, in particular for preventing and/or limiting the formation of free radicals and/or removing the free radicals present in cells; in addition, the invention relates to a composition comprising at least one extract of Vitreoscilla filiformis and lycopene.
专利号:US-2003224077-A1 优先权日:2002-04-08 标 题:Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase
专利号:US-7662997-B2 优先权日:2004-12-30 标 题 :Synthesis and applications of 2-oxo-4-methylthiobutyric acid, its salts and its derivatives 发明人:REY PATRICK; BLANCHARD GILBERT 权利人:ADISSEO IRELAND LTD 摘要:The invention relates to a process for preparing 2-oxo-4-methylthiobutyric acid (I), its salts and its derivatives n n n n n n n n n n n n in which R represents a group chosen from COOH, COOR′, NH 2 , NHR′ or NR′R″, where R′ and R″ are chosen, independently of one another, from the group of linear or branched alkyl radicals having from 1 to 12 carbon atoms and cycloalkyl radicals having from 3 to 12 carbon atoms, n according to which process but-3-ene-1,2-diol (II) is catalytically and selectively oxidized to give 2-oxobut-3-enoic acid (III) and methyl mercaptan is selectively condensed with 2-oxobut-3-enoic acid (III). n 2-Oxo-4-methylthiobutyric acid (I), its salts and its derivatives are used as food supplement, in particular in animal nutrition.
专利号:US-2007237746-A1 优先权日:2002-04-08 标题:Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase
专利号:US-2010291007-A1 优先权日:2002-04-08 标题 :Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase
专利号:EP-2153815-A1 优先权日:2008-08-05 标题 :Use of urea containing compositions 发明人:TRULLAS CABANAS CARLOS RAMON; KRUTMANN JEAN PROF DR 权利人:ISDIN SA 摘要:The present invention relates to the use of a composition comprising urea for increasing the expression of at least one gene associated with the collagen synthesis within the dermis of the skin. nThe urea composition has been used for preventing/treating damages of the skin such as signs of aging, wrinkles, damages associated with UV-radiation, wounds, skin diseases.
1: Ducrotte P, Grimaud JC, Dapoigny M, Personnic S, O'Mahony V, Andro-Delestrain MC. On-demand treatment with alverine citrate/simeticone compared with standard treatments for irritable bowel syndrome: results of a randomised pragmatic study. Int J Clin Pract. 2014 Feb;68(2):245-54. doi: 10.1111/ijcp.12333. Epub 2013 Oct 21. 2: Lee SH, Athavankar S, Cohen T, Piran R, Kiselyuk A, Levine F. Identification of alverine and benfluorex as HNF4α activators. ACS Chem Biol. 2013 Aug 16;8(8):1730-6. doi: 10.1021/cb4000986. Epub 2013 May 29. 3: Bueno L, Beaufrand C, Theodorou V, Andro-Delestrain MC. Influence of simethicone and alverine on stress-induced alterations of colonic permeability and sensitivity in rats: beneficial effect of their association. J Pharm Pharmacol. 2013 Apr;65(4):567-73. doi: 10.1111/jphp.12021. Epub 2013 Jan 17. doi: 10.1016/j.ejphar.2014.08.033. Epub 2014 Sep 6. doi: 10.1002/dta.130. doi: 10.1111/j.1365-2036.2009.04216.x. Epub 2009 Dec 10. doi: 10.3748/wjg.v20.i20.6031. Review.
合成参考文献
摘要:Journal of Hepathology., 27(399), 1997 [] 摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664 摘要:S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (2021) DOI:10.1021/acsenvironau.1c00008. List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355