CAS: 123-11-5; 4-Methoxybenzaldehyde

• 英文名称4-Methoxybenzaldehyde
• 中文名称4-甲氧基苯甲醛
• IUPAC名称4-methoxybenzaldehyde
• 其它别名Anisic Aldehyde; P-Anisaldehyde, Analytical Standard; P-Anisaldehyde (Usp-Rs); Benzaldehyde, 4-Methoxy; Benzaldehyde, 4-Methoxy-; P-Anisaldehyde, ; Anisaldehyde; Anisaldehyde (Para); Bmse
• CAS编号123-11-5
• MFCD编号:MFCD00003385
• EINECS号:204-602-6
• FDA UNII编号:9PA5V6656V
• 分子式:C8H8O2
• 分子量:136.15
• 产品CID: 333878
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• InChIKey: ZRSNZINYAWTAHE-UHFFFAOYSA-N
• InChI=1S/C8H8O2/c1-10-8-4-2-7(6-9)3-5-8/h2-6H,1H3…
• 计算化学: 氢键受体数2.0氢键供体数0.0可旋转键数2.0

相似化合物

物理性质

• 熔点-1°C
• 沸点248°C at 760 mmHg
• 闪点108°C
• 密度1.121
• PH:7 (2g/l, H2O, 20°C)
• PSA:26.3
• LogP:1.5077
• 折射率1.571-1.574
• 蒸汽压0.0±0.5 mmHg at 25°C
• 溶解性2G/l
• 敏感性空气敏感
• 外观形态透明无色至黄色液体
• 储存条件存储低于 +30°C.
• 产品应用用作香料及制造抗组织胺剂的中间体.
• 性质描述无色透明油状液体.熔点0°C,沸点249.5°C(248°C),144-200°C(28kPa),134-135°C(1.6kPa),83°C(0.267kPa),相对密度1.1191(15/4°C),折射率1.5730,闪点108°C.易溶于乙醇;乙醚;丙酮;氯仿等,溶于苯,不溶于水.能随水蒸汽挥发.

MSDS等安全信息

• GHS象形图
• GHS符号GHS08;
  注释: Health hazard
• 危险类别生殖毒性 类别2
  水生慢性毒性 类别3
  急性毒性 类别4(经口)
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  水生慢性毒性 类别2
  皮肤致敏 类别1
  严重眼刺激 类别2A
  Muta. 1A
  生殖毒性 类别1B
  特定目标器官毒性-重复接触 类别1
  特定目标器官毒性-重复接触 类别2
  皮肤腐蚀 类别1
  易燃液体 类别2
• 警示词Warning(警告)
• 危险描述H361fd |怀疑会影响生育能力. 怀疑对胎儿造成损害.
  H412 |对水生生物有害并具有长期持续影响.
  H302 |吞咽有害.
  H361d |怀疑对胎儿造成损害.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H361 |怀疑对生育能力或胎儿造成损害.
  H411 |对水生生物有毒并具有长期持续影响.
  H317 |可能引起皮肤过敏反应.
  H340 |可能导致遗传缺陷.
  H360 |可能损害生育能力或胎儿.
  H336 |可能引起嗜睡或头晕.
  H372 |长期或反复接触损害器官.
  H373 |长期或反复接触可能损害器官.
  H314 |造成严重皮肤灼伤和眼损伤.
  H226 |易燃液体和蒸气.
• 防范说明P273-P280-P405-P501
• 危险等级IRRITANT
• UN编号1988
• 危险品标志Xn,Xi,T,F
• 安全声明26-36-45-36/37-16-7
• 危险类别码22-36/37/38-39/23/24/25-23/24/25-11-R22-36/38
• WGK Germany1

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 P-Anisaldehyde 主要起始原料 4-Methoxybenzyl Bromide
• 105-13-5 = 123-11-5
  反应条件:1.1C:2048-37-5,C:1109-15-5,S:Mecn,7 H,Rt
  标题:Discovery Of The Quinoxalinone-B(C6F5)3.H2O Combo As A Photocatalyst By Acidochromism Strategy: Aerobic Oxidation Of Alcohol,Alkene,And Thiols
  作者:By Huang,Jie Et Al
  参考文献:Organic Letters 日期:2023 卷标:25(30) 页码:5613-5618]
  
  105-13-5 = 123-11-5 + 38493-59-3
  反应条件:1.1R:Me4-Piperidoxyl,R:Nabr,R:Nahco3,S:H2O,S:Ch2Cl2
  标题:Lessons From An Array: Using An Electrode Surface To Control The Selectivity Of A Solution-Phase Chemical Reaction
  作者:By Feng,Enqi Et Al
  参考文献:Angewandte Chemie 日期:2022 卷标:61(10) 页码:E202116351]
  
  105-13-5 = 123-11-5
  反应条件:1.1C:39368-32-6,C:Tio2,S:H2O,4 H,Rt
  标题:Facile Preparation Of Cubi2O4/tio2 Hetero-Systems Employed For Simulated Solar-Light Selective Oxidation Of 4-Methoxybenzyl Alcohol Model Compound
  作者:By Djaballah,Ahmed Malek Et Al
  参考文献:Molecular Catalysis 日期:2023 卷标:546 页码:113251]
  
  696-62-8 = 123-11-5
  反应条件:1.1R:Phsih3,R:Et3N,C:29934-17-6,C:19437-26-4,S:Dmf,18 H,75°C
  标题:Palladium-Catalyzed Reductive Formylation Of Aryl Iodides With Co2 Under Mild Conditions
  作者:By Li,Dan Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(8) 页码:5231-5237]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:T-Buok,C:2922795-44-4,S:Phme,24 H,50°C
  标题:Alcohol Dehydrogenation-Triggered Selective C3-Alkylation Of Indoles By Homogeneous Azo-Aromatic Cobalt Catalysts
  作者:By Kamal Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(9) 页码:5827-5843]
  
  637-69-4 = 123-11-5
  反应条件:1.1R:O2,C:Nan3,S:H2O,16 H,Rt
  标题:Photo-Induced Cleavage Of Alkenes To Carbonyls In Water
  作者:By Yue,Xiaoguang Et Al
  参考文献:Asian Journal Of Organic Chemistry 日期:2023 卷标:12(6) 页码:E202300124]
  
  104-93-8 = 123-11-5
  反应条件:1.1R:T-Buooh,C:64554-19-4,S:Me(Ch2)8Me,37 H,30°C
  标题:Selective Peroxygenase-Catalysed Oxidation Of Toluene Derivates To Benzaldehydes
  作者:By Wang,Yutong Et Al
  参考文献:Chemcatchem 日期:2023 卷标:15(13) 页码:E202300645]
  
  100-06-1 = 123-11-5
  反应条件:1.1R:C5H5N,R:Seo2,110°C1.2R:HCL,S:H2O,Ph 22.1R:Bu4N+ -Oac,C:2867607-77-8,C:22693-41-0,S:Clch2Ch2Cl,8 H,35-40°C
  标题:Visible-Light Photoredox-Catalyzed Decarboxylation Of α-Oxo Carboxylic Acids To C1-Deuterated Aldehydes And Aldehydes
  作者:By Hu,Chun-Hong And Li,Yang
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(10) 页码:6401-6406]
  
  105-13-5 = 123-11-5
  反应条件:1.1C:2923917-23-9 (Nonstoichiometric),S:Phme,24 H,343K,1 Atm
  标题:Reversible Low-Temperature Redox Activity And Selective Oxidation Catalysis Derived From The Concerted Activation Of Multiple Metal Species On Cr And Rh-Incorporated Ceria Catalysts
  作者:By Ikemoto,Satoru Et Al
  参考文献:Physical Chemistry Chemical Physics 日期:2019 卷标:21(37) 页码:20868-20877]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:Koh,C:2920937-52-4,S:M-C6H4Me2,5 H,120°C
  标题:Synthesis And Structural Characterization Of Palladium Pincer Complexes: Sustainable Synthesis Of Benzothiazoles
  作者:By Anandaraj,Pennamuthiriyan Et Al
  参考文献:Applied Organometallic Chemistry 日期:2023 卷标:37(5) 页码:E7062]
  
  653586-50-6 = 123-11-5 + 82560-12-1
  反应条件:1.1 Reagents: Potassium Hydroxide Solvents: Dimethylformamide; -10 °C; 20 Min,-10 °C1.2 Reagents: Hydroxylamine-O-Sulfonic Acid; -10 °C; -10 °C -> Rt; 2 H,Rt
  标题:Synthesis And Chemistry Of 3-Tert-Butyl-1,5-Diaminopyrazole
  作者:Blake,Alexander J.; Et Al
  参考文献:Organic & Biomolecular Chemistry 日期:2003 卷标:1(23) 页码:4268-4274]
  
  530-62-1 + 696-62-8 = 123-11-5
  反应条件:1.1S:Thf,15 Min,Rt; 1 H,Rt2.1R:Et3N,C:Pd2(Dba)3,S:Dmf,5 H,70°C
  标题:Use Of Carbonyldiimidazole As An Activator Of Formic Acid In A Tris(Dibenzylideneacetone)Dipalladium-Catalyzed Formylation Of Aryl Iodides
  作者:By Nadhagopal,Sundar Et Al
  参考文献:Synlett 日期:2023 卷标:34(15) 页码:1809-1813]
  
  104-46-1 = 123-11-5
  反应条件:1.1R:O2,C:693794-98-8,S:Mecn,12 H,Rt
  标题:Visible Light Photocatalysis For Aerobic Oxidative Cleavage Of Alkenes
  作者:By Li,Huili Et Al
  参考文献:Tetrahedron Letters 日期:2023 卷标:125 页码:154624]
  
  126443-12-7 = 123-11-5 + 13195-79-4
  反应条件:1.1R:Bromosuccinimide,C:Cu(Cf3So3)2,S:Me2Co,S:H2O,3 H,Rt2.1C:Cu(Cf3So3)2,C:150529-93-4,S:Me2Co,1 H,Rt2.2R:Bromosuccinimide,30 Min,Rt
  标题:Kinetic Resolution Of Electron-Deficient Bromohydrins Via Copper(Ii)-Catalyzed C-C Bond Cleavage
  作者:By Choudhary,Kavita Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(16) 页码:12041-12053]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:O2,C:2952542-28-6,S:Mecn,12 H,Rt -> 120°C,0.8 Mpa
  标题:Additive-Free Selective Oxidation Of Aromatic Alcohols With Molecular Oxygen Catalyzed By A Mixed-Valence Polyoxovanadate-Based Metal-Organic Framework
  作者:By Tian,Hongrui Et Al
  参考文献:Dalton Transactions 日期:2023 卷标:52(26) 页码:9121-9130]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:O2,C:1361312-45-9,C:K2Co3,C:Me4-Piperidoxyl,S:Dmso,6 H,40°C
  标题:Copper Pyrithione (Cupt)-Catalyzed Oxidation Of Secondary And Primary Benzyl Alcohols With Molecular Oxygen Or Air Under Mild Conditions
  作者:By Peng,Qionghui Et Al
  参考文献:Catalysis Letters 日期:2023 卷标:153(9) 页码:2665-2673]
  
  105-13-5 = 123-11-5
  反应条件:1.1C:1416881-52-1,C:19788-49-9,S:Acoet,3 H,Rt
  标题:Photochemical Hydrogen Atom Transfer Catalysis For Dehydrogenation Of Alcohols To Form Carbonyls
  作者:By Yang,Xiaona Et Al
  参考文献:Organic Letters 日期:2023 卷标:25(29) 页码:5486-5491]
  
  105-13-5 = 123-11-5
  反应条件:1.1S:Mecn,5 H,28°C,1 Bar; 30 Min,28°C
  标题:Molten Salt Synthesis Of A Highly Crystalline Graphitic Carbon Nitride Homojunction From A Deep Eutectic Solvent For Selective Photocatalytic Oxidation
  作者:By Chen,Yanglin Et Al
  参考文献:Journal Of Materials Chemistry A: Materials For Energy And Sustainability 日期:2023 卷标:11(23) 页码:12342-12353]
  
  4180-23-8 = 123-11-5
  反应条件:1.1R:R:O2,C:9029-60-1
  标题:Co-Oxidative Transformation Of Piperine To Piperonal And 3,4-Methylenedioxycinnamaldehyde By A Lipoxygenase From Pleurotus Sapidus
  作者:By Krahe,Nina-Katharina Et Al
  参考文献:Chembiochem 日期:2021 卷标:22(19) 页码:2857-2861]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:T-Buooh,C:327-97-9 (Complex With Copper),C:Cu (Complex With Chlorogenate),30 Min,45°C
  标题:Dual Role Of Chlorogenic Acid As An Influential Precursor In Synthesizing Nano-Sized Cu(Ii) Complexes And Investigating Its Catalytic Role In The Oxidation Of Alcohols And Its Antibacterial Activity
  作者:By Shafaghatlonbar,Masoud And Bagherzade,Ghodsieh
  参考文献:Journal Of Organometallic Chemistry 日期:2023 卷标:996 页码:122758]
  
  100-09-4 = 123-11-5
  反应条件:1.1C:Cucl,C:Me4-Piperidoxyl,S:Dmso
  标题:Development And Pilot Scale Implementation Of Safe Aerobic Cu/tempo Oxidation In A Batch Reactor
  作者:By Lemaitre,Sylvain Et Al
  参考文献:Green Chemistry 日期:2023 卷标:25(14) 页码:5698-5711]
  
  637-69-4 = 123-11-5
  反应条件:1.1R:O2,C:2937334-19-3,S:Meoh,S:Mecn,72 H,25°C,0.1 Mpa
  标题:Designing Polyoxometalate-Based Metal-Organic Framework For Oxidation Of Styrene And Cycloaddition Of Co2 With Epoxides
  作者:By Yan,Xiaomei Et Al
  参考文献:Chinese Chemical Letters 日期:2023 卷标:34(7) 页码:107851]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:Me4-Piperidoxyl,R:O2,C:Fe(No3)3,S:Acoh,90 H,80°C,1 Bar
  标题:Honeycomb Reactor: A Promising Device For Streamlining Aerobic Oxidation Under Continuous-Flow Conditions
  作者:By Hosoya,Masahiro Et Al
  参考文献:Beilstein Journal Of Organic Chemistry 日期:2023 卷标:19 页码:752-763]
  
  2186-92-7 = 123-11-5 + 115240-92-1
  反应条件:1.1C:2515173-80-3 (Deprotected),S:H2O,S:Dmso,2 H,90°C
  标题:Mixtures Of Acid- And Base-Functionalized Microparticles For One-Pot Cascade Reaction
  作者:By Chen,Chen Et Al
  参考文献:Macromolecular Rapid Communications 日期:2023 卷标:44(12) 页码:2300063]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:H2O2,C:89485-18-7,4 H,65°C
  标题:Selective Oxidation Of Alcohols Promoted By Cis-Dioxomolybdenum (Vi) Ono Complexes
  作者:By Liu,Xiaoxia Et Al
  参考文献:Afinidad 日期:2023 卷标:80(598) 页码:35-50]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:O2,C:20344-49-4,C:Cds,S:Mecn,30 Min,19-21°C; 2 H,19-21°C
  标题:Selectively Permeable Feooh Amorphous Layer Coating Cds For Enhancing Photocatalytic Conversion Of Benzyl Alcohol And Selectivity To Benzaldehyde
  作者:By Li,Yan Et Al
  参考文献:Chemsuschem 日期:2023 卷标:16(9) 页码:E202202355]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:T-Buooh,C:2927523-66-6,30 Min,Rt
  标题:Quercetin As A Precursor For The Synthesis Of Novel Nanoscale Cu (Ii) Complex As A Catalyst For Alcohol Oxidation With High Antibacterial Activity
  作者:By Moodi,Zahra Et Al
  参考文献:Bioinorganic Chemistry And Applications 日期:2021 卷标:From Bioinorganic Chemistry And Applications 页码:8818452]
  
  637-69-4 = 123-11-5
  反应条件:1.1R:O2,C:15243-48-8,S:Clch2Ch2Cl,14 H,Rt
  标题:Visible-Light Photocatalytic Aerobic C=c Bond Cleavage Of Alkenes To Carbonyls By Cspbbr3 Nanocrystals
  作者:By Fan,Qiangwen Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(11) 页码:7391-7400]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:Koh,C:2924718-43-2,S:Phme,10 H,80°C; 80°C -> 23°C1.2R:HCL,S:H2O
  标题:A Catecholaldimine-Based Niii-Complex As An Effective Catalyst For The Direct Conversion Of Alcohols To Trans-Cinnamonitriles And Aldehydes
  作者:By Sharma,Vivek Et Al
  参考文献:Journal Of Organic Chemistry 日期:2023 卷标:88(11) 页码:7448-7453]
  
  105-13-5 = 123-11-5
  反应条件:1.1R:O2,C:7787-59-9,S:Mecn,2 H,Rt
  标题:Chelated Ion-Exchange Strategy Toward Biocl Mesoporous Single-Crystalline Nanosheets For Boosting Photocatalytic Selective Aromatic Alcohols Oxidation
  作者:By Li,Wei Et Al
  参考文献:Advanced Materials (Weinheim 日期:2023 卷标:35(18) 页码:2300396]
  
  403-42-9 + 105-13-5 = 123-11-5 + 81170-13-0
  反应条件:1.1 Reagents: 2,6-Lutidine ,Tetrabutylammonium Bromide ,Tetrabutylammonium Perchlorate ,Tempo Solvents: Acetonitrile; 5.5 H,5 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; Acidified
  标题:Pairing Electrocarboxylation Of Unsaturated Bonds With Oxidative Transformation Of Alcohol And Amine
  作者:Zhang,Xin; Et Al
  参考文献:Chemsuschem 日期:2023 卷标:16(19)

海关参考信息

• 2905110000-甲醇
  2912110000-甲醛
  2912210000-苯甲醛
  2908199090-其他酚的卤化衍生物
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

专利信息

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
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