专利号:US-10793495-B2 优先权日:2015-08-14 标 题:Synthesis of polyaryl substituted aryl compounds 发明人:BOULOS RAMIZ; FEUTRILL JOHN 权利人:BOULOS & COOPER PHARMACEUTICALS PTY LTD 摘要:A method for the synthesis of a aryl compound of Formula (1).n nU T-W—R 1 ) n    (1)
专利号:US-2022144750-A1 优先权日:2020-11-12 标 题 :Double alkoxycarbonylation of dienes as one-pot synthesis 发明人:YANG JI; JACKSTELL RALF; BELLER MALTHIAS; FRANKE ROBERT 权利人:EVONIK OPERATIONS GMBH 摘要:Process for the double alkoxycarbonylation of dienes as one-pot synthesis.
专利号:US-5663397-A 优先权日:1995-09-14 标 题 :Cyclic silyl enol ethers and method of preparing the same 发明人:YAMASHITA HIROSHI; TANAKA MASATO 权利人:AGENCY IND SCIENCE TECHN 摘要:There is disclosed a method of preparing cyclic silyl enol ethers (1-oxa-2-sila-5-cyclohexenes), comprising reacting a silacyclobutane with an acid halide in the presence of a palladium catalyst and an organic base. There is also disclosed novel cyclic silyl enol ethers obtained by the above method. The above cyclic silyl enol ethers belong to a new class of silyl enol ethers which are useful in the production of medicines and agricultural chemicals, and they can be used as intermediates of fine chemicals or as various reagents for fine synthesis.
专利号:US-12202782-B2 优先权日:2020-11-19 标 题:Processes and intermediates for preparing MCL1 inhibitors 发明人:DIXON DARRYL D; ISCHAY MICHAEL A; JOHNSON TREVOR C; MERIT JEFFREY E; REGENS CHRISTOPHER S; STANDLEY ERIC A; STEINHUEBEL DIETRICH P 权利人:GILEAD SCIENCES INC 摘要:The present disclosure relates to methods and intermediates for the synthesis of certain compounds that inhibit MCL1, for use in the treatment of cancers.
专利号:KR-20230134489-A 优先权日:2021-01-20 标题:Synthesis of polyfluorinated aryl and heteroaryl carboxamides
专利号:EP-4281436-A1 优先权日:2021-01-20 标题 :Synthesis of polyfluorinated aryl and heteroaryl carboxamides
摘要:L794: Wikipedia. Palladium. Last Updated 14 June 2009. 摘要:L798: International Programme on Chemical Safety (IPCS) INCHEM (2002). Environmental Health Criteria for Palladium. 摘要:A21: Smith DR, Kahng MW, Quintanilla-Vega B, Fowler BA: High-affinity renal lead-binding proteins in environmentally-exposed humans. Chem Biol Interact. 1998 Aug 14;115(1):39-52.