专利号:US-9550704-B2 优先权日:2012-05-24 标 题 :Method for synthesizing radiopharmaceuticals using a cartridge 发明人:CHI DAE YOON; LEE BYOUNG SE; LEE JAE HAK; CHU SO YOUNG; JUNG WOON JUNG 权利人:FUTURECHEM CO LTD 摘要:The present invention relates to a method for synthesizing a radiopharmaceutical using a cartridge, which makes it possible to carry out several steps of reaction required for synthesizing a radiopharmaceutical in the cartridge filled with a polymer. A method for synthesizing a radiopharmaceutical according to the present invention enables each step's reaction to be carried out with the solution confined in the cartridge so as not to flow out, thus being simplified compared to the conventional methods for synthesizing radiopharmaceuticals, and expediting the synthesis thereof.
参考标题:Synthesis And Spectral Properties Of 4-Amino- And 4-Acetylamino-N-Arylnaphthalimides Containing Electron-Donating Groups In The N-Aryl Substituent 作者:P. A. Panchenko,Yu. V. Fedorov,O. A. Fedorova,V. P. Perevalov,G. Jonusauskas |发布日期:2009.6 摘要:A Method For The Synthesis Of N-Aryl-Substituted 4-Amino- And 4-Acetylaminonaphthalimide Derivatives With Mono- And Dialkoxy Groups Or A 15-Crown-5 Moiety In The N-Aryl Substituent Is Described. The Introduction Of Electron-Donating Alkoxy Groups Into The Benzene Ring Of The N-Aryl Fragment Results In Fluorescence Quenching Of The Naphthalimide Chromophore, Which Is Most Pronounced In The Spectra Of N-Acetyl Derivatives. The Photophysical Properties Of The Synthesized 4-Amino- And 4-Acetylaminonaphthalimides Depend On The Solvent Polarity And Its Specific Solvating Ability Due To H-Bonding. The Crown-Containing Compounds Are Promising Fluorescent Chemosensors For Metal Cations.