CAS: 111076-66-5; 2,3,5,6,8,9,11,12-Octahydrobenzo[b][1,4,7,10,13]Pentaoxacyclopentadecin-15-Amine Hydrochloride

该化合物是一种合成化合物,属于一种冠状醚类别,是环状化合物,以其选择性绑定碳化物的能力而著称,这种特定化合物具有15个成员环状结构,既含有醚和矿的功能,又具有增强其溶解性和约束力的特性;氨基组的存在允许与蚂蚁和其他极分子进行潜在互动,使其在各种应用中有用,包括离子选择性电极和提取过程;作为盐类,它通常比其自由基质形式更容易溶于水中,便于其在水环境中使用;该化合物的特点往往是它能够形成金属离子的复合体,可以在分析化学和材料科学中加以利用;此外,其结构特征有助于其在药物运载系统和协调化学中的潜在应用;在处理和储存方面,应参考安全数据,如任何化学物质一样.

结构式图片

欧盟法规

ECHA物质C&L通报

合成工艺路线路线简述

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    专利信息


    专利号:US-9550704-B2
    优先权日:2012-05-24
    标 题 :Method for synthesizing radiopharmaceuticals using a cartridge
    发明人:CHI DAE YOON; LEE BYOUNG SE; LEE JAE HAK; CHU SO YOUNG; JUNG WOON JUNG
    权利人:FUTURECHEM CO LTD
    摘要:The present invention relates to a method for synthesizing a radiopharmaceutical using a cartridge, which makes it possible to carry out several steps of reaction required for synthesizing a radiopharmaceutical in the cartridge filled with a polymer. A method for synthesizing a radiopharmaceutical according to the present invention enables each step's reaction to be carried out with the solution confined in the cartridge so as not to flow out, thus being simplified compared to the conventional methods for synthesizing radiopharmaceuticals, and expediting the synthesis thereof.

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    主要参考文献

    参考标题:Synthesis And Spectral Properties Of 4-Amino- And 4-Acetylamino-N-Arylnaphthalimides Containing Electron-Donating Groups In The N-Aryl Substituent
    作者:P. A. Panchenko,Yu. V. Fedorov,O. A. Fedorova,V. P. Perevalov,G. Jonusauskas |发布日期:2009.6
    摘要:A Method For The Synthesis Of N-Aryl-Substituted 4-Amino- And 4-Acetylaminonaphthalimide Derivatives With Mono- And Dialkoxy Groups Or A 15-Crown-5 Moiety In The N-Aryl Substituent Is Described. The Introduction Of Electron-Donating Alkoxy Groups Into The Benzene Ring Of The N-Aryl Fragment Results In Fluorescence Quenching Of The Naphthalimide Chromophore, Which Is Most Pronounced In The Spectra Of N-Acetyl Derivatives. The Photophysical Properties Of The Synthesized 4-Amino- And 4-Acetylaminonaphthalimides Depend On The Solvent Polarity And Its Specific Solvating Ability Due To H-Bonding. The Crown-Containing Compounds Are Promising Fluorescent Chemosensors For Metal Cations.
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