3-C-β-D-Glucopyranosyl-4-O-β-D-Glucopyranosyliriflophenone置于盐酸,水体系中,化学反应 24.0H,反应生成鸢尾酚酮 3-C-Beta-D-吡喃葡萄糖苷
参考文献:Benzophenone C-And O-Glucosides From Cyclopia Genistoides (Honeybush) Inhibit Mammalian α-Glucosidase
标题:Benzophenone C-And O-Glucosides From Cyclopia Genistoides (Honeybush) Inhibit Mammalian α-Glucosidase
摘要:An Enriched Fraction Of An Aqueous Extract Prepared From The Aerial Parts Of Cyclopia Genistoides Vent. Yielded A New Benzophenone Di-C,O-Glucoside,3-C-β-D-Glucopyranosyl-4-O-β-D-Glucopyranosyliriflophenone (1),Together With Small Quantities Of A Known Benzophenone C-Glucoside,3-C-β-D-Glucopyranosylmaclurin (2). The Isolated Compounds Showed α-Glucosidase Inhibitory Activity Against An Enzyme Mixture Extracted From Rat Intestinal Acetone Powder. Compound 2 Exhibited Significantly (P < 0.05) Higher Inhibitory Activity (54%) Than 1 (43%) At 200 μm. In Vitro Tests In Several Cell Models Showed That 1 And Its 3-C-Monoglucosylated Derivative (3-C-β-D-Glucopyranosyliriflophenone) Were Marginally Effective (P >= 0.05) In Increasing Glucose Uptake.
Doi:10.1021/np5007247