CAS: 57531-37-0; 2-Chloro-5-Nitroimidazole

相似化合物

3034-38-6 3034-38-6 57531-38-1

上下游产品

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2,4-二硝基咪唑置于盐酸体系中,用 水 作为反应溶剂,以92%的收率获得产物2-氯-4-硝基咪唑
参考文献:Synthesis Of New Generation Triazolyl-And Isoxazolyl-Containing 6-Nitro-2,3-Dihydroimidazooxazoles As Anti-Tb Agents: In Vitro,Structure-activity Relationship,Pharmacokinetics And In Vivo Evaluation
标题:Synthesis Of New Generation Triazolyl-And Isoxazolyl-Containing 6-Nitro-2,3-Dihydroimidazooxazoles As Anti-Tb Agents: In Vitro,Structure-activity Relationship,Pharmacokinetics And In Vivo Evaluation
摘要:有前途的硝基咪唑噁唑骨架提供了另一种新颖的三唑基含有的6-硝基-2,3-二氢咪唑噁唑作为抗结核病的先导化合物.
DOI:10.1039/c5Ob00054H

专利信息

专利号:US-8129544-B2
优先权日:2002-10-15
标题:1-substituted-4-nitroimidazole compound and method for preparing the same
发明人：GOTO FUMITAKA; TAKEMURA NORIAKI; OTANI TADAAKI; HASEGAWA TAKESHI; TSUBOUCHI HIDETSUGU; UTSUMI NAOTO; FUJITA SHIGEKAZU; KURODA HIDEAKI; SHITSUTA TAKUYA; SASAKI HIROFUMI
权利人:GOTO FUMITAKA; TAKEMURA NORIAKI; OTANI TADAAKI; HASEGAWA TAKESHI; TSUBOUCHI HIDETSUGU; UTSUMI NAOTO; FUJITA SHIGEKAZU; KURODA HIDEAKI; SHITSUTA TAKUYA; SASAKI HIROFUMI; OTSUKA PHARMA CO LTD
摘要:The present invention relates to a 1-substituted-4-nitroimidazole compound represented by the general formula (1) or a salt thereof, n n(wherein R is a hydrogen atom, a lower alkoxy group-substituted lower alkyl group, a phenyl-lower alkoxy group-substituted lower alkyl group, a cyano-substituted lower alkyl group, a phenyl-lower alkyl group which may have lower alkoxy groups as the substituents in the phenyl ring or a group of the formula —CH 2 R A ; X is a halogen atom or a group of the formula —S(O)n-R 1 ) and method for preparing the same. The compound of the formula (1) is a useful compound as an intermediate for synthesis of various pharmaceutical and agricultural chemicals, particularly, as intermediates for antitubercular agents.

专利号:US-2013078185-A1
优先权日:2010-05-31
标题:Nitroimidazole derivatives
发明人：KUNIYIL KULANGARA VIJAYA RAJ; ATREYA CHANDAN RAMASWAMY
权利人:KUNIYIL KULANGARA VIJAYA RAJ; ATREYA CHANDAN RAMASWAMY; GE HEALTHCARE LTD
摘要:The present invention provides novel compounds useful in the treatment and diagnosis of mycobacterial infections. Compounds of the present invention have enhanced biological properties as compared to the related known compounds. The present invention also provides a precursor compound useful in the synthesis of certain compounds of the invention, and a method to obtain these compounds using said precursor compound. Methods of treatment and diagnosis in which the compounds of the invention fmd use are also provided.

专利号:CN-107915747-A
优先权日:2017-11-17
标 题:Synthesis of PA‑824