CAS: 42371-63-1; 9-[(1S,3S,4R,5S)-4,6,6-Trimethyl-3-Bicyclo[3.1.1]Heptanyl]-9-Borabicyclo[3.3.1]Nonane

专利信息

专利号:US-4727146-A
优先权日:1980-07-03
标题 :Synthesis of chiral 1-benzyl-1,2,3,4-tetra-hydroisoquinolines by asymmetric reduction
发明人：RICE KENNER C
权利人:US HEALTH
摘要:In a short total synthesis of morphinan compounds, derivatives of 1-benzyl-1,2,3,4-tetrahydroisoquinoline are produced. Certain of these compounds, although highly aromatic and functionalized, can be optically resolved. The optically active enantiomers can serve as important intermediates for both natural and unnatural opioids. As a special function of this invention, certain of the derivatives, namely 4'-6' and 7'-9', may be hydrogenated to 1'-3' derivative by asymmetric reduction either of the catalytic or chemical type.

专利号:US-8969596-B2
优先权日:2008-08-14
标题:Synthesis of equol
发明人：STEFFAN BERT
权利人:STEFFAN BERT
摘要:Subject of the invention is a method for the production of isoflavanes from isoflavones, whereby in a first reaction step (a) the 4-keto group of the isoflavone is reduced in a enantioselective manner, whilst the 2,3-double bond is maintained, to the 4-hydroxy compound.

专利号:US-2012094336-A1
优先权日:2008-08-14
标题:Synthesis of equol

专利号:EP-2324004-B1
优先权日:2008-08-14
标 题:Synthesis of equol