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CAS号929301-98-4 2,8-二氮杂螺[4.5]癸烷... | CAS号336191-16-3 2-B°C-8-苄基-2,8-... | CAS号34702-66-4 8-benzyl-3-oxa-... | CAS号3612-20-2 N-苄基-4-哌啶酮 | CAS号1463-52-1 2-(1-苄基-4-哌啶基)-... | CAS号40117-92-8 4-Piperidineace... | CAS号86945-27-9 1-苄基-4-氰甲基哌啶-4-甲腈 | CAS号336191-15-2 8-苄基-2,8-二氮杂螺[4.5]癸烷 | CAS号336191-14-1 8-benzyl-2-(4-m... | CAS号336191-13-0 2-[(4-甲氧基苯基)甲基]... | CAS号742067-22-7 8-(甲基磺酰基)-2,8-二... | CAS号742067-24-9 8-乙酰基-2,8-二氮杂螺[...8-苄基-2,8-二氮杂-螺[4,5]葵烷置于pd(Oh)2/c 氢气,三乙胺体系中,用 乙醇,溶剂黄146,N,N-二甲基甲酰胺 用作溶剂,20.0~50.0 °C,344.75 Kpa 条件下,反应 22.0H,反应生成2-Boc-2,8-二氮杂-螺[4.5]癸烷
参考文献:Wo2007/140383
标题:Wo2007/140383
海关参考信息
- 2905122000-异丙醇
2905143000-叔丁醇
2912110000-甲醛
2915110000-甲酸 - 💡 提示:海关信息按照顺序优先匹配,如需确认的海关信息,请参考相关资料。
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专利信息
专利号:US-12441733-B2
优先权日:2018-03-26
标题:Substituted 2,4-dioxotetrahydropyrimidines as intermediates in the synthesis of bruton's tyrosine kinase inhibitors
发明人:ARISTA LUCA; HEBACH CHRISTINA; HOLLINGWORTH GREGORY JOHN; HOLZER PHILIPP; IMBACH-WEESE PATRICIA; LORBER JULIEN; MACHAUER RAINER; SCHMIEDEBERG NIKO; VULPETTI ANNA; ZOLLER THOMAS
权利人:NOVARTIS AG
摘要:The invention relates to compounds of the formulae (I), (III), (IIIa), (XXIa), (XXIII), and/or (XLVI)or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined in the specification; to intermediates in the preparation of the compounds, to pharmaceutical compositions comprising the compounds and to use of the compounds in the treatment of disease.
专利号:CN-114249680-B
优先权日:2022-01-10
标 题:A kind of indole derivative and its synthesis method and application