CAS: 236406-39-6; 8-Boc-2,8-Diazaspiro[4.5]Decane

相似化合物

851325-42-3 1523571-85-8 336191-17-4

上下游产品

CAS号236406-38-5 4-(2-羟基乙基)-4-(羟... | CAS号1061682-96-9 2-(1-甲基乙基)-2,8-...

N-Boc-4-哌啶甲酸乙酯置于四氧化锇,Lithium Aluminium Tetrahydride,Palladium 10% On Activated Carbon,Ammonium Formate,三乙酰氧基硼氢化钠,Lithium Hexamethyldisilazane体系中,用 四氢呋喃,甲醇,水 用作溶剂,化学反应 6.58H,反应生成2,8-二氮杂螺[4.5]癸烷-8-羧酸叔丁酯
参考文献: Spirocyclic Derivatives[fr] Dérivés Spirocycliques
标题: Spirocyclic Derivatives[fr] Dérivés Spirocycliques
摘要:本发明提供了式(I)的化合物:包含这种化合物的组合物;在治疗中使用这种化合物(例如在通过抑制多巴胺转运体改善的疾病,紊乱或状况的治疗或预防);以及使用这种化合物治疗患者的方法;其中r1,R2,R3,R4,R5,R6,R9,R10,Q,X,Y,Z,A,L,B,M,N和p如本文所定义.

专利信息

专利号:US-2022363662-A1
优先权日:2021-04-20
标题 :Compounds as lxr agonists
发明人：PUJALA BRAHMAM; SATHE BALAJI DASHRATH; DANODIA ABHINANDAN; GUPTA ASHU; SONI SANJEEV; KUMAR VIVEK; ANSARI AMANTULLAH; KHAN FARHA; SARKAR ARINDAM; PAYGHAN PAVAN V
权利人:INTEGRAL BIOSCIENCES PRIVATED LTD
摘要:The present invention generally discloses compounds having LXR (the liver X receptor) agonistic activity, to the use of such compounds in the treatment of various disorders such as proliferative disorders, Alzheimer's disease, inflammatory diseases, and diseases characterized by defects in cholesterol and lipid metabolism. Specifically, the present invention discloses compound of formula (IA) which exhibit LXR agonist activity, specifically to LXRβ. The invention also discloses method of synthesis of said compounds, method of using said compounds, pharmaceutical compositions comprising said compounds and method of using thereof.

专利号:WO-0200584-A1
优先权日:2000-06-28
标题 :Cyclic ketones, their preparation and their use in the synthesis of amino acids

专利号:CN-102731500-A
优先权日:2012-06-15
标题:Synthesis of 2-(1-benzylpiperidine)-2,8-diazaspiro[4,5]decane

专利号:EP-1296921-A1
优先权日:2000-06-28
标 题 :Cyclic ketones, their preparation and their use in the synthesis of amino acids