CAS: 2237-36-7; 2-Hydroxy-4-Methoxybenzoic Acid

上下游产品

CAS号100-09-4 对甲氧基苯甲酸 | CAS号89-86-1 2,4-二羟基苯甲酸 | CAS号77-78-1 硫酸二甲酯 | CAS号91-52-1 2,4-二甲氧基苯甲酸 | CAS号5446-02-6 4-甲氧基水杨酸甲酯 | CAS号150-19-6 3-甲氧基苯酚 | CAS号298-14-6 碳酸氢钾 | CAS号77376-36-4 trans-β-deuteri... | CAS号71917-42-5 2-Hydroxy-2-(2-... | CAS号109563-16-8 2-hydroxy-4-met... | CAS号106203-25-2 2-(4-fluorophen... | CAS号490-64-2 2,4,5-三甲氧基苯甲酸 | CAS号15198-08-0 2-hydroxy-4-met... | CAS号91-52-1 2,4-二甲氧基苯甲酸 | CAS号41697-08-9 2-羟基-4-甲氧基苯碳酰肼 | CAS号98437-41-3 5-溴-2-羟基-4-甲氧基苯甲酸 | CAS号6745-77-3 4-甲氧基水杨酰胺 | CAS号673-22-3 2-羟基-4-甲氧基苯甲醛 | CAS号5446-02-6 4-甲氧基水杨酸甲酯

2,4-二甲氧基苯甲酸置于哌嗪体系中,用 N,N-二甲基乙酰胺 用作溶剂,化学反应 0.2H,以89%的收率获得4-甲氧基水杨酸
参考文献:Regioselective Dealkylation Of 2-Alkoxybenzoic Acid And Its Amide Derivatives With Aliphatic Amines
标题:Regioselective Dealkylation Of 2-Alkoxybenzoic Acid And Its Amide Derivatives With Aliphatic Amines
摘要:邻甲氧基苯甲酸与脂肪族胺在非烷基双极性溶剂中发生裂解反应.当使用二甲基乙酰胺中的哌嗪时,这种裂解反应尤其顺利.这种方法适用于邻烷氧基苯甲酸及其酰胺衍生物的各种脱烷反应,具有很高的区域选择性.
Doi:10.1055/s-2000-6244

专利信息

专利号:US-6180830-B1
优先权日:1995-11-08
标题 :Method for preparing a bimetallic ruthenium/tin catalyst and a process for the synthesis of aldehydes
发明人：JACQUOT ROLAND
权利人:RHODIA CHIMIE SA
摘要:The present invention relates to a new process for the preparation of a bimetallic ruthenium/tin catalyst. The process for the preparation of a bimetallic ruthenium/tin catalyst according to the invention is characterised by the fact that it consists in carrying out the reduction of a ruthenium complex having an electrovalency of -4 and a coordination number of 6, the ligands being either a halogen atom or an anion or a tin halide. The catalyst is further employed for the preparation of aldehydes by reduction, in the vapor phase, of carboxylic acids, esters and anhydrides.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-9453037-B2
优先权日:2011-07-28
标 题 :Methylphenidate-prodrugs, processes of making and using the same
发明人：GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB
权利人:KEMPHARM INC; KEMPHARM INC
摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.

专利号:WO-2024054881-A1
优先权日:2022-09-07
标题:Ligand-enabled scalable c-h hydroxylation of benzoic and phenylacetic acids at room temperature
发明人：YU JIN-QUAN; LI ZHEN; PARK HAN
权利人:SCRIPPS RESEARCH INST
摘要:The application discloses industry scalable methods of using bifunctional bidentate pyridone-carboxylic acid ligands, such as 2-methyl-2-(6-oxo-1,6-dihydropyridin-2-yl)propanoic acid, that enable room-temperature Pd-catalyzed C-H hydroxylation of a broad range of benzoic and phenylacetic acids with an industry-compatible oxidant, aqueous hydrogen peroxide, at room temperature. Further disclosed are methods of derivatization of the resulting hydroxylation products, synthesis of polyfluorinated natural products coumestan or pterocarpene from phenol building blocks, and hydroxylation of ibuprofen using this methodology,

专利号:US-8889863-B2
优先权日:2010-07-16
标题:Stereoselective methods, catalysts and intermediates for the synthesis of (−)-Nutlin-3 and related compounds
发明人：JOHNSTON JEFFREY N; DAVIS TYLER A
权利人:JOHNSTON JEFFREY N; DAVIS TYLER A; UNIV VANDERBILT
摘要:The present invention provides methods and intermediates are provided for the preparation of (−)-Nutlin-3. Methods and intermediates are also provided for the enantioselective addition of aryl nitromethanes to aldimines. Bis(amidine) catalysts for the use in these and other reactions are also provided.

专利号:WO-2011158333-A1
优先权日:2010-06-15
标题 :Zederone analogue and method for synthesizing same
发明人：SUETSUGU KAZUHIRO; MORITA SATOSHI; YAMADA YASUHIRO; OHNO TOSHINOBU; ITO TAKATOSHI; IWAI TOSHIYUKI; MATSUMOTO FUKASHI
权利人:NARIS COSMETICS CO LTD; OSAKA MUNICIPAL TECH RES INST; SUETSUGU KAZUHIRO; MORITA SATOSHI; YAMADA YASUHIRO; OHNO TOSHINOBU; ITO TAKATOSHI; IWAI TOSHIYUKI; MATSUMOTO FUKASHI
摘要:The present invention provides a method for synthesizing a zederone analogue derived from natural materials, a precursor useful in synthesis of the zederone analogue, and an intermediate useful for synthesizing the zederone precursor. Specifically, the present invention uses (E) -5-halegeno-4-hexanoic acid alkyl ester as a starting material to synthesize a zederone analogue, a precursor useful in synthesis of the zederone analogue, and an intermediate useful for synthesizing the zederone precursor.