CAS: 17797-10-3; 2-(4-Fluorophenyl)Propan-2-Amine

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CAS号1194-02-1 对氟苯腈 | CAS号917-54-4 甲基锂 | CAS号403-33-8 对氟苯甲酸甲酯 | CAS号1000141-64-9 1-(2-azidopropa... | CAS号403-39-4 4-氟异丙基苯 | CAS号64798-46-5 p-fluoro-α,α-di... | CAS号402-41-5 2-(4-氟苯基)-2-丙醇 | CAS号403-42-9 对氟苯乙酮

📜4-氟苯乙酮置于盐酸,氯化亚砜,Zinc(II) Chloride体系中,用 四氢呋喃,水 用作溶剂,化学反应 1.0H,反应生成1-(4-氟苯基)-1-甲基乙胺
参考文献:Sato,Kazuo; Honma,Toyokuni; Sugai,Soji,Agricultural And Biological Chemistry,1985,Vol. 49,# 12,P. 3563-3568
标题:Sato,Kazuo; Honma,Toyokuni; Sugai,Soji,Agricultural And Biological Chemistry,1985,Vol. 49,# 12,P. 3563-3568

专利信息

专利号:EP-1966146-B1
优先权日:2005-12-20
标题 :4,5-dihydro- (1h)-pyrazole derivatives as cannabinoid cb1 receptor modulators
发明人：LANGE JOSEPHUS H M; VAN DER NEUT MARTINA A W; VAN VLIET BERNARD J; IWEMA BAKKER WOUTER I
权利人:ABBOTT HEALTHCARE PRODUCTS BV
摘要:This invention is directed to 4,5-dihydro -(1 H)-pyrazole (pyrazoline) derivatives as cannabinoid CB1 receptor modulators, to pharmaceutical compositions containing these compounds, to methods for the preparation of these compounds, methods for preparing novel intermediates useful for their synthesis, and methods for preparing compositions. The invention also relates to the uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in disorders in which CB1 receptors are involved, or that can be treated via manipulation of those receptors. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification.