CAS: 15485-65-1; 2-(4-Hydroxyphenyl)-1-(2,4,6-Trihydroxyphenyl)Ethanone

相似化合物

17720-60-4 3669-41-8 487-49-0

染料木素置于sodium Hydroxide体系中,用65%的收率获得2,4,6-三羟基苯基-4'-羟基苄基甲酮
参考文献:Synthesis,Crystal Structure And Antimicrobial Activity Of Deoxybenzoin Derivatives From Genistein
标题:Synthesis,Crystal Structure And Antimicrobial Activity Of Deoxybenzoin Derivatives From Genistein
摘要:A Series Of Deoxybenzoin Derivatives From Genistein Were Synthesized And Their Structures Were Elucidated By H-1 NMR,Mass Spectral Data And Micro Analyses. The Structures Of 2,7 And 10 Were Determined By Single-Crystal X-Ray Analysis. These Obtained Compounds Were Evaluated For Their Assayed Antibacterial (Bacillus Subtilis,Escherichia Coli,Pseudomonas Fluorescence And Staphylococcus Aureus) And Antifungal (Aspergillus Niger,Candida Albicans And Trichophyton Rubrum) Activities By Mtt (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyl Tetrazolium. Bromide) Method. Most Compounds Have Displayed Comparable Antibacterial Activity Against Bacterial. On The Basis Of The Biological Results,Structure-Activity Relationships Are Discussed. (C) 2007 Elsevier Masson Sas. All Rights Reserved.
Doi:10.1016/j.Ejmech.2007.05.013

专利信息

专利号:US-2009062555-A1
优先权日:2007-08-28
标 题 :Synthesis of Isoflavone
发明人：HARMS ARTHUR E
权利人:HARMS ARTHUR E
摘要:The invention provides a process of manufacturing an isoflavone of the general formula 7 n n n n n n n n n n wherein R 1 , R 2 , R 3 , and R 4 each independently are H, OH, or an alkoxy, provided at least one of R 1 , R 2 , R 3 , and R 4 being OH, and one being alkoxy, or at least 2 groups being OH, comprising providing ketone (3) n n n n n n n n n n wherein R 1 , R 2 , R 3 , and R 4 are as stated above, combining (3) with trialkylortho formate, and a Lewis or Bronsted acid to produce the isoflavone, precipitating the isoflavone.