CAS: 13730-09-1; 2,5-Dimethylbenzonitrile

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610-72-0 5779-94-2 21789-36-6

上下游产品

CAS号553-94-6 2,5-二甲基溴苯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号143-33-9 氰化钠 | CAS号1122-42-5 1,4-二甲基-2-碘苯 | CAS号53957-33-8 2,5-二甲基苯甲醇 | CAS号544-92-3 氰化亚铜 | CAS号106-42-3 对二甲苯 | CAS号143814-17-9 (6-cyanato-9,10... | CAS号610-72-0 2,5-二甲基苯甲酸 | CAS号625-86-5 2,5-二甲基呋喃 | CAS号93-48-1 2,5-二甲基苄胺 | CAS号5779-94-2 2,5-二甲基苯甲醛 | CAS号610-72-0 2,5-二甲基苯甲酸 | CAS号160039-16-7 2,5-bis(bromome... | CAS号2142-73-6 2',5'-二甲基苯乙酮 | CAS号87662-75-7 1-amino-3,7-dim...

📜2,5-二甲基苯甲醇置于ammonium Hydroxide,碘体系中,化学反应 6.0H,以80%的收率获得2,5-二甲基苯甲腈
参考文献:在nh 3水溶液中用分子碘和dih将醇和胺直接氧化为腈
标题:在nh 3水溶液中用分子碘和dih将醇和胺直接氧化为腈
摘要:用分子碘在氨水溶液和1,3-二碘-5,5-二甲基乙内酰脲中成功地进行了简单且高收率的方法,将各种伯醇以及伯,仲和叔胺直接氧化转化为相应的腈分别在nh 3水溶液中.
Doi:10.1016/j.Tet.2007.05.106

专利信息

专利号:US-2004152905-A1
优先权日:2003-01-31
标题:Universal building blocks and support media for synthesis of oligonucleotides and their analogs
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and chemically modified oligonucleotide analogs, are provided. In addition, methods for functionalization of a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-6653468-B1
优先权日:2002-07-31
标 题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
权利人:ISIS PHARMACEUTICALS INC
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-2002147331-A1
优先权日:2001-02-02
标题:Methods for synthesis of oligonucleotides
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:The present invention is directed to improved methods and compositions for synthesis of oligonucleotides and other phosphorus-linked oligomers, without the need for phosphoryl protecting groups. The methods involve the reaction of nucleoside phosphoramidites with a support-bound oligomer having one or more unprotected phosphorus-containing internucleoside linkages in the presence of a neutralizing agent.

专利号:US-9045521-B2
优先权日:2012-07-31
标 题 :Synthesis of deuterated ribo nucleosides N-protected phosphoramidites, and oligonucleotides
发明人：SRIVASTAVA SURESH C; YASKO AMY
权利人:SRIVASTAVA SURESH C; YASKO AMY; ASED LLC
摘要:The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.