CAS: 1035490-58-4; Tert-Butyl (S)-(1-(3-Fluorophenyl)-2-Hydroxyethyl)Carbamate
- 英文名称Tert-Butyl (S)-(1-(3-Fluorophenyl)-2-Hydroxyethyl)Carbamate
- 中文名称(S)-(1-(3-氟苯基)-2-羟乙基)氨基甲酸叔丁酯
- IUPAC名称tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate
- 其它别名Carbamic Acid, N-[(1S)-1-(3-Fluorophenyl)-2-Hydroxyethyl]-, 1,1-Dimethylethyl Ester; (S)-1-(3-Fluoro-Phenyl)-2-Hydroxy-Ethyl]-Carbamic Acid Tert-Butyl Ester; Tert-Butyl N-[(1S)-1-(3-Fluorophenyl)-2-Hydroxyethyl]Carbamate; Tert-Butyl (S)-(1-(3-Fluorophenyl)-2-Hydroxyethyl)Carbamate; (S)-2-(Boc-Amino)-2-(3-Fluorophenyl)Ethanol
- CAS编号1035490-58-4
- MFCD编号:MFCD29076508
- EINECS号:962-148-0
- 分子式:C13H18FNO3分子量:255.29
- 产品CID: 70230
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
欧盟法规
C&L通报合成工艺路线路线简述
- 合成目标产物 Tert-Butyl (S)-(1-(3-Fluorophenyl)-2-Hydroxyethyl)Carbamate 主要起始原料 Di-Tert-Butyl Dicarbonate And (2S)-2-Amino-2-(3-Fluorophenyl)Ethan-1-Ol Hcl
- (文献来源)合成步骤主要原料 Di-Tert-Butyl Dicarbonate 和 (2S)-2-Amino-2-(3-Fluorophenyl)Ethan-1-Ol Hcl
海关参考信息
- 2905199090-其他饱和一元醇
2905399099-其他二元醇
2905499000-其他多元醇
2905590090-其他无环醇的卤化、磺化等衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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专利信息
专利号:US-11780834-B2
优先权日:2018-06-21
标题:Solid forms of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3- yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol and processes for preparing fused tricyclic compounds comprising a substituted phenyl or pyridinyl moiety, including methods of their use
发明人：CHUNG CHEOL KEUN; XU JIE; IDING HANS; CLAGG KYLE; DALZIEL MICHAEL; FETTES ALEC; GOSSELIN FRANCIS; LIM NGIAP-KIE; MCCLORY ANDREW; ZHANG HAIMING; CHAKRAVARTY PAROMA; NAGAPUDI KARTHIK; ROBINSON SARAH
权利人:HOFFMANN LA ROCHE; GENENTECH INC
摘要:Provided herein are solid forms, salts, and formulations of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol, processes and synthesis thereof, and methods of their use in the treatment of cancer.
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📌 第三方产品分析报告
合成参考文献
参考文献:10.1055/s-0032-1316797
摘要:Kikelj D, Trstenjak U, Ilaš J. Advances in the Synthesis of Morpholin-3-ones and Morpholin-2-ones. Synthesis. 2012 Nov 05;44(23):3551–78. doi: 10.1055/s-0032-1316797.
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