CAS: 944401-75-6; 3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Pyridin-2-Amine
该化合物是的碳酸酯衍生物,作为有机合成和制药研究的多种中间体.三点的氟替代会增强其在交叉反应中的回作用,如铃木-宫村交织,而2-氨基组则提供了进一步功能化的处理器. 醇双柱酸混合物在环境条件下确保稳定,便利处理和储存. 由于生物活性分子,农用化学品和材料科学具有平衡的再活动性和结构灵活性,这种化合物在生物活性分子,农用化学品和材料科学的开发方面特别有价值. 它的高纯度和清晰的结构使它成为复杂的分子结构的可靠建筑块.
- 英文名称3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Pyridin-2-Amine
- 中文名称3-氟-5-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)吡啶-2-胺
- IUPAC名称3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
- 其它别名2-氨基-3-氟吡啶-5-硼酸频那醇酯; 3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-2-Pyridinamine
- CAS编号944401-75-6
- MFCD编号:MFCD12923417
- EINECS号:827-260-5
- 分子式:C11H16BFN2O2分子量:238.07
- 产品CID: 1994934
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
相似化合物
827614-64-2 1310404-43-3 2096331-68-7物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
bis(pinacol)diborane 5-bromo-3-fluoro-pyridin-2-ylamine 3-fluoropyridin-2-amine 3-(6-amino-5-fluoropyridin-3-yl)-N-(4-cyanophenyl)-N-methylpyrazolo[1,5-a]pyridine-5-carboxamide合成工艺路线路线简述
- 合成目标产物 3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Pyridin-2-Amine 主要起始原料 2-Amino-3-Fluoropyridine
- 73183-34-3 + 748812-37-5 = 944401-75-6
反应条件:1.1 Reagents: Potassium Acetate Catalysts: 1,1-Bis(Diphenylphosphino)Ferrocene,[1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane; Overnight,100 °C
标题:Preparation Of Spiro Compounds As Map4K1 Inhibitors
参考文献:World Intellectual Property Organization]
73183-34-3 + 748812-37-5 = 944401-75-6
反应条件:1.1 Reagents: Potassium Acetate Catalysts: Dichloro[1,1′-Bis(Diphenylphosphino)Ferrocene]Palladium(Ii) Dichloromethane Addu... Solvents: 1,4-Dioxane; 16 H,85 °C
标题:Preparation Of Pyrazolopyridine Compounds For The Treatment Of Parasitic Diseases
参考文献:World Intellectual Property Organization]
73183-34-3 + 748812-37-5 = 944401-75-6
反应条件:1.1 Reagents: Potassium Acetate Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane; 4 H,Rt -> 100 °C
标题:Preparation Of Imidazolopyridines And -Pyrimidines As Tricyclic Dlk Inhibitors And Uses Thereof
参考文献:World Intellectual Property Organization]
73183-34-3 + 748812-37-5 = 944401-75-6
反应条件:1.1 Reagents: Potassium Acetate Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane; 4 H,Rt -> 100 °C
标题:Preparation Of Pyrazolylpyridinamine Derivatives For Use As Dlk Inhibitors
参考文献:World Intellectual Property Organization]
73183-34-3 + 748812-37-5 = 944401-75-6
反应条件:1.1 Reagents: Potassium Acetate Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane,Water; 17 H,Rt -> 90 °C
标题:Small Molecule Compound As Efficient And Specific Jak Kinase Inhibitor
参考文献:World Intellectual Property Organization]
89402-44-8 + 73183-34-3 = 944401-75-6
反应条件:1.1 Reagents: Ammonia Solvents: Isopropanol; 30 Min,195 °C1.2 Reagents: Potassium Acetate Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane; 15 H,90 °C
标题:1H-Imidazo[4,5-C]Quinolinone Compounds As Protein Kinase Inhibitors And Their Preparation And Use In The Treatment Of Proliferative Diseases
参考文献:World Intellectual Property Organization
📜2-氨基-3-氟吡啶置于(1,1'-Bis(Diphenylphosphino)Ferrocene)Palladium(II) Dichloride,N-溴代丁二酰亚胺(Nbs),Potassium Acetate体系中,用 1,4-二氧六环,乙腈 作为反应溶剂,化学反应 20.0H,反应生成 3-氟-5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)吡啶-2-胺
参考文献:一种小分子化合物
标题:一种小分子化合物
摘要:本发明提供的一种小分子化合物,其特征在于,为由如下分子通式所示的结构:其中,所述x1,X2选自碳或氮;所述g1为具有芳香性的碳环或杂环;所述g1环上的,任一或任几个氢原子为r1所取代;所述r1选自含氮基团.本发明的小分子化合物可作为高效和特异的jak激酶抑制剂,特别是tyk2抑制剂,和/或jak1抑制剂,和/或jak1/tyk2或tyk2/jak1,Tyk2/jak2双重抑制剂.
海关参考信息
- 2905122000-异丙醇
2905143000-叔丁醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
