CAS: 7773-83-3; 1-Docosanethiol

该化合物是一种有机化合物,其特点是长链脂质结构,其特点是具有硫醇(-SH)功能组的长链脂质结构,分子式为C22H46S,由由22个碳原子组成的直链碳氢化合物脊柱组成.该化合物一般在室内温度下无色可粉黄液,呈现出一种特殊的硫化气味.Dosane-1-thiol在水中不溶,但在有机溶剂中可溶解,这是长链硫醇常见的.它以其在有机合成中的应用为著名,特别是在制作硫醇-甲基聚合物时,以及由于其非物理性质而具有潜在的表面活性.此外,Docosane-1-thol可以参与各种化学反应,包括氧化成分硫化物或磺酸.其稳定性和再活性使有机溶剂在长期链硫溶剂中都具有可溶性,这是常见的,在工业和研究环境中,特别是在生产材料和化学安全时,这种化学和化学的防能中应观测.

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CAS号6938-66-5 1-溴二十二烷

合成工艺路线路线简述

    1-溴二十二烷置于氢氧化钾体系中,用 四氢呋喃 作为反应溶剂,化学反应 18.5H,反应生成 1-二十二烷基硫醇
    参考文献:Carotene As A Molecular Wire: Conducting Atomic Force Microscopy
    标题:Carotene As A Molecular Wire: Conducting Atomic Force Microscopy
    摘要:A Conducting Atomic Force Microscope Was Used To Measure The Electrical Properties Of Carotenoid Molecules Attached To A Gold Electrode. The Thiolated Carotene Molecules Were Embedded In Insulating N-Alkanethiol Self-Assembled Monolayers. At A Contact Force Of A Few Nanonewtons,A Carotenoid Molecule Behaves Ohmically With A Resistance Of Approximately 4.2 +/-0.7 G Ohm; Over A Million Times More Conductive Than An Alkane Chain Of Similar Length. Modes Of Electron Transport Are Discussed.
    DOI:10.1021/jp9831278

    海关参考信息

    专利信息


    专利号:US-10730904-B2
    优先权日:2012-11-14
    标 题:Method for liquid-phase synthesis of nucleic acid
    发明人:NONOGAWA MITSURU; NAGATA TOSHIAKI; SAITO HIDEKI; YASUMA TSUNEO
    权利人:TAKEDA PHARMACEUTICALS CO
    摘要:In this method, an oligonucleotide represented by formula (II) [wherein Y 1 , Q, Base, r and r′ are each as defined in claim 1 ] is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R 1 , Y, Base, Z, Ar, R 2 , R 3 and n are each as defined in claim 1 ]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3′-direction but also in the 5′-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.

    专利号:US-2015315229-A1
    优先权日:2012-11-14
    标 题 :Method for liquid-phase synthesis of nucleic acid

    专利号:US-2019135852-A1
    优先权日:2012-11-14
    标题 :Method for liquid-phase synthesis of nucleic acid

    专利号:EP-2921499-A1
    优先权日:2012-11-14
    标 题 :Method for liquid-phase synthesis of nucleic acid

    专利号:EP-2921499-B1
    优先权日:2012-11-14
    标 题 :Method for liquid-phase synthesis of nucleic acids
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    合成参考文献


    参考文献:10.1007/978-3-322-80133-3_4
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