CAS: 5891-53-2; H-Glu-Lys-Oh

该化合物是一种由氨酸甲基酸和甘油构成的二酸二酸二酸,其特征是,氨基甘酸碳酸组和氨基甘油组之间形成了一种氨酸联系,该化合物通常存在于各种生物系统中,在蛋白合成和新陈代谢中发挥作用.Glutamylysine展示了peptides的共同特性,如水溶性以及形成氢结壳的能力,这对其生物活动有帮助.它也可能参与各种生物化学途径,包括...

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L-lysine L-glutamic acid L-Lysine hydr°ChlorideL-lysine L-glutamic acid

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    专利号:US-6281331-B1
    优先权日:1998-03-23
    标 题 :Methods and compositions for peptide synthesis
    发明人:KANG MYUNG-CHOL; BRAY BRIAN; LICHTY MAYNARD; MADER CATHERINE
    权利人:TRIMERIS INC
    摘要:The present invention relates, first, to methods for the synthesis of peptides, in particular T-20 (also referred to as 'DP-178'; SEQ ID NO:1) and T-20-like peptides. Such methods utilize solid and liquid phase synthesis procedures to synthesize and combine groups of specific peptide fragments to yield the peptide of interest. The present invention further relates to individual peptide fragments which act as intermediates in the synthesis of the peptides of interest (e.g., T-20). The present invention still further relates to groups of such peptide intermediate fragments which can be utilized together to produce full length T-20 and T-20-like peptides.

    专利号:US-5962294-A
    优先权日:1992-03-09
    标题 :Compositions and methods for the identification and synthesis of sialyltransferases
    发明人:PAULSON JAMES C; WEN XIAOHONG; LIVINGSTON BRIAN; GILLESPIE WILLIAM; KELM SORGE; BURLINGAME ALMA L; MEDZIHRADSZKY KATALIN
    权利人:UNIV CALIFORNIA; CYTEL CORP
    摘要:DNA isolates coding for sialyltransferase which contain a conserved region of homology and methods of obtaining such DNA are provided, together with expression systems for recombinant production of sialyltransferase.

    专利号:US-5401844-A
    优先权日:1983-04-11
    标 题 :Regulation of enzymes which utilize tetrahydrobiopterin or tetrahydrofolate cofactors with 6,6-disubstituted-tetrahydropteridines
    发明人:AYLING JUNE E; BAILEY STEVEN W
    权利人:UNIV SOUTH ALABAMA
    摘要:6-[2'-Amino-2',2'-disubstituted-ethylamino]-pyrimidines of the structure: ##STR1## in which X=H, NH 2 or NO 2 , which are novel intermediates in the synthesis of quinoid 6,6-disubstituted-dihydro- and 6,6-disubstituted-tetrahydro-pteridines, are claimed.

    专利号:SK-635190-A3
    优先权日:1989-12-20
    标题:Bcrf1 protein of epstein-barr virus being capable of inhibiting synthesis of gamma-interferon, expression vector for synthesis thereof, and pharmaceutical composition containing thereof

    专利号:US-2017349628-A1
    优先权日:2014-10-02
    标 题:Synthesis of Cell Penetrating Peptides for Drug Delivery and Stem Cell Applications

    专利号:WO-2024233408-A1
    优先权日:2023-05-05
    标 题 :Compositions comprising kombucha and their uses
    发明人:DOUCET OLIVIER; PUJOS MURIEL; CHAMAYOU-ROBERT CECILE
    权利人:COTY INC; JOYAL DAVID; DOUCET OLIVIER; PUJOS MURIEL; CHAMAYOU ROBERT CECILE
    摘要:The invention is generally directed to identification and use of a kombucha extract, alpha-glucan oligosaccharide, or a mixture thereof that is capable of increasing skin barrier protection as assessed by ability to increase cell differentiation certain biomarkers of as measured by expression of filaggrin and involucrin in particular. A composition may be used in a method of improving an aesthetic appearance of skin of a human affected by weakened skin barrier comprising topically applying thereto a therapeutically effective amount of an active agent, wherein the active agent increases synthesis of involucrin and/or filaggrin by greater than 40% when applied ex vivo to human skin keratinocytes at a concentration of at least 0.45% w/w in a cosmetically acceptable vehicle.

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    合成参考文献


    参考文献:10.1021/jm0511029
    摘要:Vig BS, Stouch TR, Timoszyk JK, Quan Y, Wall DA, Smith RL, Faria TN. Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding. J Med Chem. 2006 Jun 15;49(12):3636–44. doi: 10.1021/jm0511029.
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