CAS: 502-95-4; Tetrahydro-3,6-Pyridazinedione

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CAS号123-33-1 马来酰肼 | CAS号21827-92-9 n,n'-diacetylgl... | CAS号17973-86-3 3,6-二溴哒嗪 | CAS号3741-24-0 (1,1-Bipyrrolid... | CAS号65886-43-3 1,2-dimethyldia... | CAS号5343-01-1 see Pyridazino[...

📜抑芽丹置于乙醇,Aluminium Amalgam体系中,化学反应生成 四氢-3,6-吡嗪二酮
参考文献:The Reactions Of Succinic Anhydride With Hydrazine Hydrate1,2,3
标题:The Reactions Of Succinic Anhydride With Hydrazine Hydrate1,2,3
摘要:
DOI:10.1021/ja01154A068

专利信息

专利号:US-9850275-B2
优先权日:2013-09-11
标 题 :Photolabile linker for the solid-phase synthesis of hydrazides and pyranopyrazoles
发明人：NIELSEN THOMAS E; QVORTRUP KATRINE
权利人:UNIV DANMARKS TEKNISKE
摘要:The photolabile hydrazine linker of the present invention is based on the o-nitro-veratryl group, which is capable of releasing hydrazide derivatives upon UV irradiation. The linker allows for a new solid-phase peptide synthesis (SPPS) strategy which is fully orthogonal to the most commonly used protecting groups and chemical methods in SPPS and shows excellent compatibility with peptide composition, notably the 20 naturally occurring α-amino acid residues (even in their side-chain protected form) are accepted in the C-terminal of the peptide hydrazides. Furthermore, the linker unit can be applied to synthesize combinatorial libraries of biological interesting heterocyclic compounds, such as pyranopyrazoles.

专利号:US-2010137244-A1
优先权日:2006-07-13
标题 :Preparation and utility of hmg-coa reductase inhibitors
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:Chemical syntheses and medical uses of novel modulators of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and diastereomeric mixtures of isomers, individual diastereomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of hypercholesterolemia, dyslipidemia, coronary artery disease, atherosclerosis, metabolic syndrome, a hyperproliferative disease such as colorectal cancer, prostate cancer, and melanoma, a neurodegenerative disease such as cerebral ischemia, Alzheimer's disease, and Parkinson's disease are described.

专利号:EP-3044204-B1
优先权日:2013-09-11
标 题 :A photolabile linker for the solid-phase synthesis of hydrazides and pyranopyrazoles

专利号:US-2023095750-A1
优先权日:2019-12-12
标 题:Flow chemistry synthesis of isocyanates
发明人：BURKART MICHAEL D; PHUNG HAI THIEN AN
权利人:UNIV CALIFORNIA
摘要:The disclosure provides, inter alia, safe and environmentally-friendly methods, such as flow chemistry, to synthesize isocyanates, such as methylene diphenyl diisocyanate, toluene diisocyanate, hexamethylene diisocyanate, isophorone diisocyanate, and tetramethylxylene diisocyanate.

专利号:CA-2922332-A1
优先权日:2013-09-11
标 题 :A photolabile linker for the solid-phase synthesis of hydrazides and pyranopyrazoles

专利号:US-2016272672-A1
优先权日:2013-09-11
标题:Photolabile linker for the solid-phase synthesis of hydrazides and pyranopyrazoles