CAS: 4673-26-1; Diphenyleneiodonium Chloride

该化合物是一种有机碘化合物,其独特结构特征是碘原子中枢,与两个苯基组和氯化离子结合,通常被作为黄色至橙色晶状固体体体遇到.新闻部因其作为各种生物过程的强大抑制剂的作用而著称,特别是在红氧化反应的情况下,它作为电子接受器发挥作用.该化合物经常用于生物化学研究,研究氧化性压力和细胞信号路径.它的再活性是由于碘原子的存在,它可以参与各种化学反应,包括涉及核分裂剂的化学反应.此外,新闻部在有机溶剂中溶解,但水溶性有限.在处理该化合物时,应当采取安全防范措施,因为它可能是有毒和刺激剂.总的来说,二苯乙烯氯化物是化学和生物研究的宝贵工具,可以了解氧化性损害和细胞反应机制.

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CAS号54147-90-9 2-氨基-2’-碘联苯 | CAS号32174-73-5 5-phenyl-5H-5λ3... | CAS号2236-52-4 2,2'-二碘代联苯 | CAS号244-54-2 DIPHENYLENEIODO... | CAS号14498-95-4 2'-氯联苯-2-甲酸

合成工艺路线路线简述

    📜2-碘联苯置于trifluoromethanesulfonate,间氯过氧苯甲酸体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.0H,以100%的收率获得产物二苯基氯化碘盐
    参考文献:Palladium Catalyzed Dual C-h Functionalization Of Indoles With Cyclic Diaryliodoniums,An Approach To Ring Fused Carbazole Derivatives
    标题:Palladium Catalyzed Dual C-h Functionalization Of Indoles With Cyclic Diaryliodoniums,An Approach To Ring Fused Carbazole Derivatives
    摘要:正如标题反应所示,在单次操作中通过吲哚与环状二芳基碘鎓的双c-H官能化反应获得了一系列二苯并咔唑化合物.
    DOI:10.1039/c4Ob02170C

    专利信息


    专利号:US-8183409-B2
    优先权日:2004-05-06
    标题:High yield and rapid synthesis methods for producing metallo-organic salts
    发明人:CHRISTGAU STEPHAN; ANDERSEN JENS E T
    权利人:CHRISTGAU STEPHAN; ANDERSEN JENS E T; OSTEOLOGIX AS
    摘要:A new method for preparing salts of metal cations and organic acids, especially divalent salts of alkaline earth metal ions from group II of the periodic system and carboxylic acids. The method comprising the use of a high temperature (about 90° or more) and, optionally. high pressure, in order to obtain a higher yield, purity and faster reaction speed than obtained with known synthesis methods. In particular, the present invention relates to the production of strontium salts of carboxylic acids. Novel strontium salts are also provided by the present method.

    专利号:US-5795574-A
    优先权日:1995-09-07
    标题:Use of an extract from a non-photosynthetic filamentous bacterium and composition containing it
    发明人:BRETON LIONEL; AUBERT LUCIEN; LECLAIRE JACQUES; MARTIN RICHARD; DE LACHARRIERE OLIVIER
    权利人:OREAL
    摘要:The present invention relates to the use of at least one extract from at least one non-photosynthetic filamentous bacterium as substance P antagonist in a cosmetic composition or for the preparation of a pharmaceutical composition. The invention also relates to the use of at least one extract from at least one non-photosynthetic filamentous bacterium in a cosmetic composition or for the preparation of a pharmaceutical composition intended for the treatment of disorders associated with an excess in the synthesis and/or in the release of substance P. The invention additionally relates to various compositions containing an extract from at least one non-photosynthetic filamentous bacterium and to a cosmetic treatment process.

    专利号:US-2024208898-A1
    优先权日:2021-03-25
    标 题 :Enamine n-oxides: synthesis and application to hypoxia-responsive prodrugs and imaging agents
    发明人:KIM JUSTIN; KANG DAHYE; CHEUNG SHELDON T
    权利人:DANA FARBER CANCER INST INC
    摘要:Disclosed are compounds and pharmaceutically acceptable salts and stereoisomers thereof that are suitable for diagnosis and the treatment of diseases and disorders characterized by, associate with or which exhibit tissue hypoxia, such as, for example, solid tumors. Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds.

    专利号:US-6146636-A
    优先权日:1997-09-22
    标题 :Substance P antagonists comprising rosaceae plant extracts
    发明人:BRETON LIONEL; PINEAU NATHALIE
    权利人:OREAL
    摘要:Disease states, disorders, conditions or afflictions manifesting excessive synthesis and/or release of substance P are therapeutically treating by administering to individuals in need of such treatment, an effective substance P antagonist amount of at least one extract of at least one plant of the Rosaceae family.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Peng JJ, Liu B, Xu JY, Peng J, Luo XJ. NADPH oxidase: its potential role in promotion of pulmonary arterial hypertension. Naunyn Schmiedebergs Arch Pharmacol. 2017 Apr;390(4):331-338. doi: 10.1007/s00210-017-1359-2. Epub 2017 Feb 11. Review. doi: 10.1016/j.autrev.2016.02.018. Epub 2016 Feb 27. Review. doi: 10.1016/j.freeradbiomed.2012.10.538. Epub 2012 Oct 17. Review. doi: 10.1113/jphysiol.2008.165597. Epub 2009 Feb 23. Review.
    5: Aldieri E, Riganti C, Polimeni M, Gazzano E, Lussiana C, Campia I, Ghigo D. Classical inhibitors of NOX NAD(P)H oxidases are not specific. Curr Drug Metab. 2008 Oct;9(8):686-96. Review. Review.

    合成参考文献


    参考文献:10.1128/aac.00996-19
    摘要:Kidwai S, Bouzeyen R, Chakraborti S, Khare N, Das S, Priya Gosain T, Behura A, Meena CL, Dhiman R, Essafi M, Bajaj A, Saini DK, Srinivasan N, Mahajan D, Singh R. NU-6027 Inhibits Growth of Mycobacterium tuberculosis by Targeting Protein Kinase D and Protein Kinase G. Antimicrob Agents Chemother. 2019 Sep;63(9).
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