📜2-碘联苯置于trifluoromethanesulfonate,间氯过氧苯甲酸体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.0H,以100%的收率获得产物二苯基氯化碘盐 参考文献:Palladium Catalyzed Dual C-h Functionalization Of Indoles With Cyclic Diaryliodoniums,An Approach To Ring Fused Carbazole Derivatives 标题:Palladium Catalyzed Dual C-h Functionalization Of Indoles With Cyclic Diaryliodoniums,An Approach To Ring Fused Carbazole Derivatives 摘要:正如标题反应所示,在单次操作中通过吲哚与环状二芳基碘鎓的双c-H官能化反应获得了一系列二苯并咔唑化合物. DOI:10.1039/c4Ob02170C
专利信息
专利号:US-8183409-B2 优先权日:2004-05-06 标题:High yield and rapid synthesis methods for producing metallo-organic salts 发明人:CHRISTGAU STEPHAN; ANDERSEN JENS E T 权利人:CHRISTGAU STEPHAN; ANDERSEN JENS E T; OSTEOLOGIX AS 摘要:A new method for preparing salts of metal cations and organic acids, especially divalent salts of alkaline earth metal ions from group II of the periodic system and carboxylic acids. The method comprising the use of a high temperature (about 90° or more) and, optionally. high pressure, in order to obtain a higher yield, purity and faster reaction speed than obtained with known synthesis methods. In particular, the present invention relates to the production of strontium salts of carboxylic acids. Novel strontium salts are also provided by the present method.
专利号:US-5795574-A 优先权日:1995-09-07 标题:Use of an extract from a non-photosynthetic filamentous bacterium and composition containing it 发明人:BRETON LIONEL; AUBERT LUCIEN; LECLAIRE JACQUES; MARTIN RICHARD; DE LACHARRIERE OLIVIER 权利人:OREAL 摘要:The present invention relates to the use of at least one extract from at least one non-photosynthetic filamentous bacterium as substance P antagonist in a cosmetic composition or for the preparation of a pharmaceutical composition. The invention also relates to the use of at least one extract from at least one non-photosynthetic filamentous bacterium in a cosmetic composition or for the preparation of a pharmaceutical composition intended for the treatment of disorders associated with an excess in the synthesis and/or in the release of substance P. The invention additionally relates to various compositions containing an extract from at least one non-photosynthetic filamentous bacterium and to a cosmetic treatment process.
专利号:US-2024208898-A1 优先权日:2021-03-25 标 题 :Enamine n-oxides: synthesis and application to hypoxia-responsive prodrugs and imaging agents 发明人:KIM JUSTIN; KANG DAHYE; CHEUNG SHELDON T 权利人:DANA FARBER CANCER INST INC 摘要:Disclosed are compounds and pharmaceutically acceptable salts and stereoisomers thereof that are suitable for diagnosis and the treatment of diseases and disorders characterized by, associate with or which exhibit tissue hypoxia, such as, for example, solid tumors. Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds.
专利号:US-6146636-A 优先权日:1997-09-22 标题 :Substance P antagonists comprising rosaceae plant extracts 发明人:BRETON LIONEL; PINEAU NATHALIE 权利人:OREAL 摘要:Disease states, disorders, conditions or afflictions manifesting excessive synthesis and/or release of substance P are therapeutically treating by administering to individuals in need of such treatment, an effective substance P antagonist amount of at least one extract of at least one plant of the Rosaceae family.
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合成参考文献
参考文献:10.1128/aac.00996-19 摘要:Kidwai S, Bouzeyen R, Chakraborti S, Khare N, Das S, Priya Gosain T, Behura A, Meena CL, Dhiman R, Essafi M, Bajaj A, Saini DK, Srinivasan N, Mahajan D, Singh R. NU-6027 Inhibits Growth of Mycobacterium tuberculosis by Targeting Protein Kinase D and Protein Kinase G. Antimicrob Agents Chemother. 2019 Sep;63(9).