CAS: 2892-62-8; 3,4-Dibutoxycyclobut-3-Ene-1,2-Dione

相似化合物

5231-87-8 61699-62-5 5222-73-1

上下游产品

CAS号2892-51-5 方酸 | CAS号71-36-3 正丁醇 | CAS号3200-96-2 全氯环丁烯酮 | CAS号588-43-2 原甲酸三丁酯 | CAS号21647-15-4 3-Cyclobutene-1... | CAS号68842-66-0 2,4-双[4-(二乙氨基)-... | CAS号61699-50-1 3-butoxy-4-(2-m... | CAS号61699-75-0 3-butoxy-4-(2-m...

方酸 以74的收率获得方酸二正丁酯
参考文献:Bioorg Med Chem. 2017,25,3803-3814
标题:Bioorg Med Chem. 2017,25,3803-3814

专利信息

专利号:WO-2016005407-A1
优先权日:2014-07-07
标 题:One-pot synthesis of squaramides
发明人：MÃ?RQUEZ LÓPEZ MARÃ?A EUGENIA; ALEGRE REQUENA JUAN VICENTE; PÉREZ HERRERA RAQUEL
权利人:UNIV ZARAGOZA; CONSEJO SUPERIOR INVESTIGACION
摘要:The present invention refers to the first one-pot synthesis of squaramides. The one-pot synthesis of squaramides described herein is an easy and straightforward procedure to obtain squaramide derivatives which saves energy, avoids time consuming purification steps, reduces costs and provides better yields as compared with those squaramides obtained through the traditional 'stop-and-go' approach. Moreover, the authors of the present invention herein demonstrate the efficiency of this one-pot process with the synthesis of three biologically active structures, improving in most of the cases the results of the previous stepwise syntheses.

专利号:US-6482950-B1
优先权日:1991-05-06
标 题 :Squarylium compounds, and processes and intermediates for the synthesis of these compounds
发明人：GARCIA PAULINA P; LEE JOHN W; MARSHALL JOHN L; MCGOWAN DONALD A; PUTTICK ANTHONY J; SPENCER THOMAS K; STROUD STEPHEN G; TELFER STEPHEN J; ZURAW MICHAEL J
权利人:POLAROID CORP
摘要:Squarylium compounds of the formula: n wherein Q 1 and Q 2 are each independently a pyrylium, thiopyrylium, selenopyrylium, benzpyrylium, benzthiopyrylium or benzselenopyrylium nucleus, and R 1 and R 2 are each independently an aliphatic or cycloaliphatic group, can be prepared by reacting a squaric acid derivative of the formula: n with a compound of the formula Q 2 CH 2 R 2 in the presence of a base. The derivatives of Formula II may be prepared by condensing a 2,3,4,4-tetrahalocyclobut-2-en-1-one with a compound of the formula Q 1 CH 2 R 1 in the presence of a base to produce a compound of the formula: n wherein Q 1 and R 1 are as defined above, and X represents chlorine or bromine, and hydrolyzing the compound of Formula III. Alternatively, the derivatives of Formula II may be prepared by reacting a diester, monoacid chloride monoester or diacid chloride of squaric acid with a compound of the formula Q 1 CH 2 R 1 in the presence of a base, followed by hydrolysis of the resultant monoacid chloride or monoester derivative of the compound of Formula II to the parent compound.

专利号:EP-0516985-B1
优先权日:1991-05-06
标 题 :Synthesis of squarylium compounds

专利号:US-5231190-A
优先权日:1991-05-06
标题:Squarylium compounds, and processes and intermediates for the synthesis of these compounds

专利号:US-5919950-A
优先权日:1991-05-06
标 题 :Squarylium compounds, and processes and intermediates for the synthesis of these compounds

专利号:EP-0516985-A1
优先权日:1991-05-06
标题 :Synthesis of squarylium compounds