专利号:EP-1383732-B1 优先权日:2001-05-04 标题:Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules 发明人:BOURGET CECILE; LHOMME JEAN; LAAYOUN ALI; KOTERA MITSUHARU; TREVISIOL EMMANUELLE; MENOU LIONEL; BERNAL MENDEZ ELOY 权利人:BIO MERIEUX; UNIV GRENOBLE 1; CENTRE NAT RECH SCIENT 摘要:The invention concerns a temperature-stable labelling reagent of formula (I), wherein: R<1> represents H or an alkyl, aryl or substituted aryl group; R<2> represents a detectable marker or at least two detectable markers linked together by at least a multimeric structure; L is a linking arm comprising a linear catemer concatenation of at least two covalent bonds; and n is an integer equal to 0 or 1; R<3> and R<4> represent, independently of each other: H, NO2, Cl, Br, F, I, R<2>-(L)n-Y-X-, OR, SR, NR2, R, NHCOR, CONHR, COOR with R = alkyl or aryl, A is a linking arm comprising at least a double bond enabling the conjugation of the diazo function with the aromatic cycle; and u is a whole number between 0 and 2, preferably between 0 and 1; and -Y-X- represents -CONH-, -NHCO-, -CH2O-, -CH2S-. The invention also concerns a method for the synthesis of said markers and uses for labelling biological molecules, in particular nucleic acids, with a labelling reagent bearing the diazomethyl function. The invention is particularly applicable in the field of diagnosis.
专利号:US-5108725-A 优先权日:1990-01-25 标题 :Synthesis of mesoporous crystalline material 发明人:BECK JEFFREY S; CHU CYNTHIA T; JOHNSON IVY D; KRESGE CHARLES T; LEONOWICZ MICHAEL E; ROTH WIESLAW J; VARTULI JAMES C 权利人:MOBIL OIL CORP 摘要:This invention relates to a method for synthesizing a new synthetic composition of ultra-large pore crystalline material which can be used as a sorbent or catalyst component for conversion of organic and inorganic compounds. The crystalline material product of this method exhibits unusually large sorption capacity demonstrated by its benzene adsorption capacity of greater than about 15 grams benzene/100 grams at 50 torr and 25° C., a hexagonal electron diffraction pattern that can be indexed with a d 100 value greater than about 18 Angstrom Units and a hexagonal arrangement of uniformly sized pores with a maximum perpendicular cross section of at least about 13 Angstrom units.
专利号:EP-2098506-B1 优先权日:2008-02-22 标题 :Production of lactams by ammoximation of cyclic ketones 发明人:HOELDERICH WOLFGANG F; ANILKUMAR METTU; SCHALLER RAINER 权利人:UHDE INVENTA FISCHER GMBH 摘要:Present invention describes the direct catalytic liquid phase synthesis of caprolactam from cyclohexanone, hydrogen peroxide and ammonia. The invention can be carried out by using mesoporous materials amongst the MMS family (mesoporous molecular sieves) as catalysts, such as Ti-MCM-41, A1-MCM-41 and Ti-SBA-15 materials at temperatures between 20 and 120 °C.
专利号:US-2014113196-A1 优先权日:2011-06-27 标题 :Synthesis of mesoporous transition metal oxides as anode materials 发明人:BALAYA PALANI; HARIHARAN SRIRAMA 权利人:BALAYA PALANI; HARIHARAN SRIRAMA; UNIV SINGAPORE 摘要:A method of preparing mesoporous nanostructured particles of a transition metal oxide. The method contains the steps of dissolving a soft-template compound in a solvent, dispersing a first or second row transition metal ion-containing compound, adjusting the pH value if necessary, and removing the solvent to obtain mesoporous nanostructured transition metal oxide powders, calcining the powders optionally to afford mesoporous nanostructured particles of the transition metal oxide. Also disclosed is particle prepared by the above-described method.
专利号:US-8871926-B1 优先权日:2010-09-28 标题:Synthesis of porphyrin nanostructures 发明人:FAN HONGYOU; BAI FENG 权利人:FAN HONGYOU; BAI FENG; SANDIA CORP 摘要:The present disclosure generally relates to self-assembly methods for generating porphyrin nanostructures. For example, in one embodiment a method is provided that includes preparing a porphyrin solution and a surfactant solution. The porphyrin solution is then mixed with the surfactant solution at a concentration sufficient for confinement of the porphyrin molecules by the surfactant molecules. In some embodiments, the concentration of the surfactant is at or above its critical micelle concentration (CMC), which allows the surfactant to template the growth of the nanostructure over time. The size and morphology of the nanostructures may be affected by the type of porphyrin molecules used, the type of surfactant used, the concentration of the porphyrin and surfactant the pH of the mixture of the solutions, and the order of adding the reagents to the mixture, to name a few variables.
专利号:US-2003138490-A1 优先权日:2001-09-08 标 题 :Synthesis and uses of polymer gel nanoparticle networks 发明人:HU ZHIBING; LU XIHUA; GAO JUN; PONDER BILL C; JOHN JOHN ST; MORO DANIEL G 摘要:Disclosed is a new class of nanostructured polymeric materials comprising polymer gel nanoparticles that are covalently bonded through functional groups on the surfaces of neighboring particles. These nanoparticles may be prepared as suspensions in an aqueous or, non-aqueous environment. These gels have two unique and different structural networks; the primary network comprises crosslinked polymer chains in each individual particle, while the secondary network is a system of crosslinked nanoparticles. Particular polymer gel nanoparticle network compositions disclosed herein may function as carriers for controlled delivery of pharmaceuticals or other chemical agents, gel sensors and other commercial applications.
参考文献:10.1007/bf00114627 摘要:van Ginkel CG. Complete degradation of xenobiotic surfactants by consortia of aerobic microorganisms. Biodegradation. 1996 Apr;7(2):151–64. doi: 10.1007/bf00114627. 参考文献:10.1007/s13361-012-0530-8 摘要:Fang Y, Liu F, Liu J. Mass Spectrometry Study of Multiply Negatively Charged, Gas-Phase NaAOT Micelles: How Does Charge State Affect Micellar Structure and Encapsulation Journal of The American Society for Mass Spectrometry. 2012 Dec 18;24(1):9–20. doi: 10.1007/s13361-012-0530-8.