CAS: 19614-16-5; (2-Bromophenyl)(Methyl)Sulfane

上下游产品

CAS号6320-02-1 2-溴苯硫醇 | CAS号74-88-4 碘甲烷 | CAS号7133-37-1 甲基硫环己酯 | CAS号583-53-9 1,2-二溴苯 | CAS号137092-17-2 2-bromobenzened... | CAS号126253-78-9 N-Acetyl-S-(4-b... | CAS号77-78-1 硫酸二甲酯 | CAS号1072-85-1 1-溴-2-氟苯 | CAS号33951-33-6 2-甲砜基溴苯 | CAS号7321-58-6 2-溴苯基甲基亚砜 | CAS号35216-39-8 3-甲砜基苯胺 | CAS号91-20-3 萘 | CAS号100-68-5 茴香硫醚 | CAS号100-66-3 苯甲醚 | CAS号634-36-6 1,2,3-三甲氧基苯 | CAS号6609-54-7 2-(甲基硫代)苯甲腈 | CAS号655-20-9 2-氟茴香硫醚 | CAS号3724-10-5 2-甲硫基苯甲酸

O-Bromobenzenediazonium置于alkali体系中,化学反应生成2-溴茴香硫醚
参考文献:Van Hove,Bulletin De La Classe Des Sciences,Academie Royale De Belgique,1926,Vol. <5>12,P. 940,941;
标题:Van Hove,Bulletin De La Classe Des Sciences,Academie Royale De Belgique,1926,Vol. <5>12,P. 940,941;

专利信息

专利号:US-5908935-A
优先权日:1996-09-18
标 题:Process for the preparation of 1-Acyl-4-arylpiperidines
发明人：BRIEDEN WALTER; LOETSCHER DIDIER; NAUGHTON ANDREW
权利人:LONZA AG
摘要:1-Acyl-4-arylpiperidines of the general formula: ##STR1## wherein R 1 is an aryl group optionally substituted by one or more C 1-6 -alkyl groups, C 1-6 -alkoxy groups, benzyloxy groups or C 1-6 -alkylthio groups and/or one or more fluorine atoms, and R 2 is a C 1-6 -alkyl group, a C 1-6 -alkoxy group, an optionally substituted aryl group, alkylaryl group or a benzyloxy group optionally substituted on the phenyl radical. The 1-acyl-4-arylpiperidines of formula I are prepared by reacting an arylmagnesium halide with a 1-acylpyridinium halide, obtainable from pyridine and an acyl halide, in the presence of a copper compound to give the corresponding 1-acyl-4-aryl-1,4-dihydropyridine, and hydrogenating the latter. The 1-acyl-4-arylpiperidines are intermediates in the synthesis of pharmaceutical active ingredients, for example, neurokinin receptor antagonists.

专利号:US-7884125-B2
优先权日:2008-04-30
标 题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:US-6495713-B2
优先权日:2001-01-17
标 题 :Synthesis of ketosulfone esters
发明人：CHEN CHENG YI; CHEN WEIRONG; O'SHEA PAUL; TAN LUSHI; TILLYER RICHARD; XU FENG; DAGNEAU PHILIPPE
权利人:MERCK & CO INC
摘要:This invention encompasses a process for making a compound of Formula A n These compounds are intermediates useful in the preparation of certain non-steroidal anti-inflammnatory agents.

专利号:US-2002143205-A1
优先权日:2001-01-17
标 题:Synthesis of ketosulfone esters

专利号:CA-2433927-A1
优先权日:2001-01-17
标 题 :Synthesis of ketosulfone esters

专利号:US-2009275616-A1
优先权日:2008-04-30
标 题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues