CAS: 14685-79-1; 2-Chloro-2-Deoxy-D-Glucose
该化合物是一种合成葡萄糖,C-2位置的氢氧基体组被氯原子所取代.这种修改具有独特的生化特性,使其成为碳水化合物化学和球菌生物学研究中有价值的中间体.化合物对于研究葡萄糖新陈代谢和酶抑制作用特别有用,因为它的结构与天然葡萄糖相似,而其氯替代作用干扰了典型的代谢途径.它作为进一步化学修改的前体,并用于开发甘蓝抑制剂和标签探测器.它的稳定性和再活动使它成为生物化学和药学研究的机械学研究的多种工具.
- 英文名称2-Chloro-2-Deoxy-D-Glucose
- 中文名称2-氯-2-脱氧-D-葡萄糖
- IUPAC名称(2R,3S,4R,5R)-2-chloro-3,4,5,6-tetrahydroxyhexanal
- 其它别名2-Chloro-Dg; 2-Cldg; 2-Chloro-2-Deoxy-D-Glucose Analog Of 2-F Luoro-2-; 2-Cidg; 2-Chloro-2-Deoxyglucose; Cldg; 2-Chloro-2-Deoxy-D-Glucose ,; Fludeoxyglucose Related Compound B (10 Mg) (2-Chloro-2-Deoxy-D-Glucose)
- CAS编号14685-79-1
- MFCD编号:MFCD01317996
- 分子式:C6H11ClO5分子量:198.6
- 产品CID: 700806
- 产品分类生物化工 → 糖类化合物 → 单糖
物理性质
MSDS等安全信息
合成工艺路线路线简述
📜O1,O3,O4,O6-Tetraacetyl-2-Chloro-D-2-Deoxy-Glucitol置于盐酸体系中,化学反应生成2-氯-2-脱氧-D-葡萄糖
参考文献:Buncel,E.; Bradley,P.R.,Canadian Journal Of Chemistry,1967,Vol. 45,P. 514-519
标题:Buncel,E.; Bradley,P.R.,Canadian Journal Of Chemistry,1967,Vol. 45,P. 514-519
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:EP-1789107-B1
优先权日:2004-08-30
标题 :Medical stent provided with inhibitors of atp synthesis
发明人：POPOWSKI YOURI
权利人:INTERSTITIAL THERAPEUTICS
摘要:The present invention relates to a stent provided with a composition comprising at least one type of inhibitor of ATP synthesis optionally together with at least one inhibitor of the pentose phosphate pathway (PPP) for use in treating stenosis and preventing restenosis in vascular ducts, and for use in treating cancerous tumours present in ducts, resectioned cavities and scars, and for use in treating any disorder arising from the proliferation of cells in ducts or cavities.
专利号:US-2007292478-A1
优先权日:2004-08-30
标 题:Medical Implant Provided with Inhibitors of Atp Synthesis
专利号:WO-2006024488-A2
优先权日:2004-08-30
标题:Medical stent provided with inhibitors of atp synthesis
专利号:US-2009324682-A1
优先权日:2004-08-30
标 题:Medical stent provided with inhibitors of atp synthesis
专利号:EP-1789107-A2
优先权日:2004-08-30
标题:Medical stent provided with inhibitors of atp synthesis
专利号:EP-1789030-A2
优先权日:2004-08-30
标 题:Medical implant provided with inhibitors of atp synthesis
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/s11307-019-01395-6
摘要:Zhu S, Mosessian S, Kroeger K, Sadeghi S, Slavik R, Kinloch S, Moore M, Allen-Auerbach M, Czernin J, Phelps M. Transforming an Academic Radiochemistry Facility for Positron Emission Tomography Drug cGMP Compliance. Molecular Imaging and Biology. 2019 Jun 25;22(2):256–64. doi: 10.1007/s11307-019-01395-6.
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